Brain Tissue Layers Reshape Ultrasound Beams in Transcranial Stimulation Models
A large-scale simulation study of 20 subjects and 13 stimulation sites shows that including the brain's soft tissue layers, not ...
Tag: blood-brain barrier
Methylmercury Rewires Brain Cell Genes at Doses That Leave Cells Alive
A new transcriptomic study reveals that non-lethal methylmercury exposure disrupts gene expression, microRNA regulation, and ion transport in rat neuronal ...
Blood-Brain Barrier Leaks Distort Brain Tumor PET Scans, Mouse Study Reveals
A mouse study shows that TSPO-PET signals in glioblastoma remain largely cell-specific early on but lose specificity as blood-brain barrier ...
Stem Cell Transplant Cured a Girl’s Leukemia but Left Her Friedreich Ataxia Unchanged
A decade-long case report shows that allogeneic stem cell transplantation cured a Friedreich's ataxia patient's leukemia and normalized her blood ...
Astrocyte Enzyme PHGDH Drives Blood Vessel Repair After Stroke
New research shows that the astrocytic enzyme PHGDH supplies serine to growing brain vessels through endothelial SLC38A2 transport and mTORC1 ...
Chalcone Library Yields Nanomolar MAO-B Inhibitors for Neurodegeneration
Researchers have identified a morpholine-substituted chalcone, TC12, that inhibits monoamine oxidase B at 11 nanomolar with over 3,600-fold selectivity and ...
Lab-Grown Brain Tumor Organoids Build Their Own Blood Vessels and Scaffolding
Researchers have grown glioblastoma organoids without any exogenous scaffold, allowing tumor stem cells to autonomously assemble neurovascular-like structures and extracellular ...
Nonprofit Accelerator Commits $1.7 Million to Five Projects Targeting Blindness, Sepsis and Rare Disease
Critical Path Institute's Translational Therapeutics Accelerator has awarded nearly $1.7 million across five BRIDGe grants to advance therapies for neuropathic ...
mRNA Therapeutics Move Beyond Vaccines Into Cancer and Rare Disease Medicine
A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...
Engineered Brain Organoids Move Toward Standardized, Translational Lab Models
A new review proposes an engineering-to-function framework linking brain organoid construction variables, vascularization strategies, and functional validation to the translational ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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