In Alzheimer-model mice, minimally invasive vagus nerve stimulation delivered right after orthopedic surgery reduced acute amyloid-beta accumulation, neuronal loss and ...
A case report describes a woman with meningococcal septic shock whose routine cerebrospinal fluid tests appeared normal while markedly elevated ...
De novo designed microproteins, built computationally to bind toxic amyloid fibrils and restore mitochondrial function, are emerging as promising candidates ...
An in vitro study finds brain microvascular endothelial cells release extracellular vesicles in a polarized manner, with apical vesicles binding ...
A new rat study reports that chitosan-coated selenium nanoparticles carrying Mucuna pruriens seed extract improved motor function, antioxidant levels, and ...
A CRISPR-engineered rat carrying a truncating Cwh43 allele developed ventricular enlargement, impaired rotarod performance and multiregional blood-brain barrier permeability phenotypes ...
A new commentary proposes that the mitochondrial protein PINK1, a central regulator of mitophagy, could act as a direct amyloid ...
A BMC Medicine review proposes a three-layer acoustic dose-control framework linking ultrasound exposure to specific brain bioeffects across ablation, barrier ...
A human stem-cell study shows that static membrane inserts and a flowing microfluidic blood-brain barrier chip give strikingly different answers ...
Researchers engineered lipid nanoparticles around the antihistamine hydroxyzine, achieving brain delivery of mRNA, CRISPR components and a radioprotective interleukin in ...
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