Phase-Separation Discovery Reveals How a Key Gene-Regulating Complex Assembles Itself
New research shows that the scaffolding protein KANSL1 forms liquid-like condensates that assemble the NSL chromatin complex and drive the ...
Tag: biomolecular condensates
Splicing factor SRSF1 tunes nucleolar cap pH to rescue ribosome factories after stress
A new Nature Chemical Biology study shows that the splicing factor SRSF1 is recruited to dark nucleolar caps under stress, ...
Tiny RNA Hubs May Steer Inflammation in Aging Cells
A new review argues that stress granules and their RNA-binding proteins act as context-dependent modulators of cellular senescence and inflammation ...
How Liquid Droplets Inside Cells May Drive Cancer—and What Drugs Could Do About It
A new review in Molecular Cancer provides a rigorous framework for how liquid–liquid phase separation drives cancer biology and evaluates ...
Liquid Droplets Inside Cells Emerge as Promising New Targets for Cancer Therapy
A new review details how dysregulated liquid–liquid phase separation drives cancer and how engineered peptides, modification mimics and synthetic condensates ...
Tiny red-light switch FenixS–Ash1 delivers ultralow-background optogenetic control
Scientists have engineered FenixS and Ash1, a compact biliverdin-binding protein pair whose binding affinity rises more than 1,200-fold under far-red ...
PhaseOM Unifies Phase-Separation Analysis and Key-Residue Detection in One Framework
Liquid–liquid phase separation, the process by which molecules spontaneously condense into concentrated droplets without a surrounding membrane, has become one ...
Phase Separation Shapes Cell Membranes and Condensates
In the intricate world within living cells, the principle of phase separation emerges as a vital mechanism that orchestrates the ...
Biomolecular Condensates in Pro-β-Carboxysome Assembly
In the intricate world of cellular biology, the assembly of biomolecular structures often reveals astonishing mechanisms that sustain life at ...
Biomolecular Condensates Maintain pH Gradients via Charge Neutralization
In a groundbreaking study poised to reshape our understanding of cellular chemistry and molecular biology, a team of researchers has ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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