Blood Cell DNA Fingerprints Could Expose Hidden Inflammation in Diseased Tissue
Researchers have identified DNA methylation markers unique to white blood cells that can quantify immune infiltration in saliva, inflammatory disease ...
Tag: Biomarkers
Benign Prostate Tissue Carries Molecular Fingerprints of Nearby Tumors, Study Finds
Swedish researchers show that gene expression in histologically benign prostate tissue systematically reflects tumor proximity, grade, and molecular subtype, suggesting ...
Antibody-DNA Hybrids Push Ultrasensitive Diagnostics and RNA Drugs Forward
A new review in LabMed Discovery surveys how antibody-oligonucleotide conjugates combine antibody targeting with nucleic acid programmability for ultrasensitive proteomics ...
New Cholesterol-Glucose Index Matches Classic Marker in Flagging Diabetic Kidney Disease
A cross-sectional study of 1,379 patients with type 2 diabetes finds that the cholesterol–high-density lipoprotein–glucose index is independently associated with ...
Appetite Hormones Stay Stubbornly Out of Sync as Anorexia Patients Gain Weight in Treatment
A Norwegian study tracking appetite-related hormones in 42 patients with anorexia nervosa during 12 weeks of inpatient treatment found that ...
Liquid Biopsy of Brain Tumors: Spinal Fluid DNA Profiling Moves Into Real-World Neuro-Oncology
A real-world study of 76 patients shows that sequencing tumor DNA in cerebrospinal fluid can diagnose mysterious brain lesions, confirm ...
Diabetes Drugs Unexpectedly Raise Levels of Gut Microbe-Linked Heart Risk Marker TMAO
A pooled analysis of two placebo-controlled crossover trials shows that the SGLT-2 inhibitors empagliflozin and dapagliflozin modestly but significantly raise ...
Bone-Seeking PET Tracer Reveals Hidden Remodeling in Ankylosing Spondylitis
A prospective Taiwanese study finds that fluorine-18 sodium fluoride PET/CT quantifies osteoblastic activity in the sacroiliac joints of ankylosing spondylitis ...
Leaking Mitochondrial DNA Emerges as a Central Engine of Cellular Aging
A new review in Biogerontology argues that leaking mitochondrial DNA activates the cGAS-STING innate immune pathway in senescent cells, sustaining ...
Truncated ALK Transcript in Solid Tumours: Hyped Biomarker or Biological Enigma?
A new narrative review concludes that the truncated ALK ATI transcript is a context-dependent biological phenomenon rather than a validated ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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