CT Scans Reveal Hidden Tumour Chaos That May Signal KRAS Mutations in Lung Cancer
A CT-based measure of spatial intratumoural heterogeneity is strongly associated with KRAS mutation status in lung adenocarcinoma, but a rigorous ...
Tag: biomarker
Bladder Cancer Protein GSDMB Boosts Immunotherapy by Recruiting Immune Cells
A new study reveals that the protein GSDMB enhances anti-PD-1 immunotherapy in bladder cancer by driving Sema7a-mediated recruitment and activation ...
ENO3 Emerges as a Lactate-Linked Biomarker in Colorectal Cancer Metastasis
Integrated transcriptomic analysis of TCGA and GEO datasets identifies a six-gene lactate metabolism signature and nominates ENO3 as a prognosis-associated ...
Hidden RNA splice variant drives colorectal cancer spread, study finds
A tumor-specific splice variant of CALD1, driven by the splicing factor hnRNPA1 and acting through the motor protein MYH9, promotes ...
Single-Cell Study Pinpoints OTUD7B as a Master Switch Behind Pancreatic Cancer’s Defenses
A multiomics study identifies the deubiquitinase OTUD7B as a central driver of epithelial remodelling, mitochondrial reprogramming, and immune suppression in ...
Acupuncture Eases Migraines but Leaves Key Biomarker CGRP Unchanged
A prospective pilot study of 52 patients with episodic migraine found significant clinical improvements after 10 sessions of manual acupuncture, ...
Uric Acid-to-HDL Ratio Predicts Carotid Atherosclerosis But Fails to Sharpen Risk Prediction
A cohort of 16,572 Chinese adults found that a higher uric acid-to-HDL-cholesterol ratio independently predicted incident carotid atherosclerosis over 2.7 ...
Vimentin Emerges as a Powerful Prognostic Marker in Triple-Negative Breast Cancer
A retrospective cohort study from Indonesia's national referral hospital links vimentin expression to dramatically shorter survival in triple-negative breast cancer ...
Small RNA Molecule Shows Promise Against Ovarian Cancer Chemoresistance
A new study shows that the microRNA-197-3p molecule, which is depleted in ovarian cancer, directly suppresses the collagen protein COL4A6 ...
Inflammation Gene Variant May Shape Survival After Rectal Cancer Therapy Choice
An exploratory analysis of a randomized trial in locally advanced rectal cancer found that an IL1B gene variant was linked ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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