Oxidative Stress Gene Signature Flags Prostate Cancer Recurrence Risk
A LASSO-based risk score built from oxidative stress-related genes predicts biochemical recurrence in prostate cancer, with LAMP5 knockdown reducing PC3 ...
Tag: biochemical recurrence
Four-Gene Signature Predicts Prostate Cancer Recurrence and Flags SPAG5 as Drug Target
A four-gene transcriptomic signature stratifies prostate cancer patients by biochemical recurrence risk and identifies SPAG5 as a targetable oncogene.
Validated HPLC and TLC methods confirm purity of zirconium-89 PSMA tracer for clinical use
Researchers validated HPLC and TLC analytical methods for measuring the radiochemical purity of the zirconium-89 labelled PSMA-I&T radiotracer ahead of ...
PSMA PET MRI Spots Prostate Cancer Recurrence in a Quarter of Men Right at the Start of Biochemical Relapse
A prospective study of 24 men found that 18F-Flotufolastat PSMA PET MRI detected recurrent prostate cancer in 25 percent of ...
Three genes tied to lactylation and lactate metabolism may flag prostate cancer recurrence risk
An integrated sequencing analysis identified MKI67, MIPEP and CCNA2 as candidate prognostic biomarkers for biochemical recurrence risk in prostate cancer.
Shorter PET/CT scans may miss prostate cancer recurrence signs in some patients
A retrospective study of 200 patients found that shortened 68Ga-PSMA PET/CT protocols miss tumor manifestations in a minority of patients ...
StereoBed trial to compare radiotherapy schedules after prostate surgery
The multicenter StereoBed trial will randomize 284 patients to compare five-fraction stereotactic radiotherapy with standard schedules after prostatectomy, with two-year ...
TCGA study links coagulation-associated lncRNAs to prostate cancer prognosis
A TCGA-based prostate cancer study developed a coagulation-associated lncRNA prognostic signature, found distinct immune-related features in high-risk patients, and showed ...
Four-gene model predicts biochemical recurrence in prostate adenocarcinoma in integrated study
A BMC Cancer abstract reports that public-dataset modeling identified a four-gene prognostic model for prostate adenocarcinoma biochemical recurrence, with supporting ...
PSMA PET Scans Guide Long-Lasting Radiation Therapy for Prostate Cancer Recurrence
A bi-institutional study of 179 patients shows PSMA PET/CT-guided salvage elective nodal radiotherapy combined with hormone therapy delivers durable five-year ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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