Review maps CRISPR-Cas9 advances in editing precision, delivery and therapeutic applications
A 2026 review summarizes advances in CRISPR-Cas9 precision, delivery and primary-cell engineering for genetic diseases and diabetes, while the available ...
Tag: base editing
Comparative chloroplast genomics reveals codon usage and phylogeny in 16 Amorphophallus species
A comparative analysis of chloroplast genomes from 16 Amorphophallus species identifies three phylogenetic clades, shared codon preferences and a five-locus ...
Donald Kohn’s Gene Therapy Breakthroughs Earn Medical Academy Honor
UCLA physician-scientist Donald Kohn’s election to the National Academy of Medicine honors decades of work advancing blood stem cell gene ...
Free-Base Editing Delivers Cleaner DNA Changes in Crops
A modular cytidine base editor that separates its Cas9 nickase and deaminase produced fewer unwanted DNA changes in moss and ...
Nanoparticles may carry CRISPR gene editing into infant neuroblastoma
Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...
Three FDA-Approved Therapies Have Transformed Spinal Muscular Atrophy, Yet Major Unmet Needs Remain
A comprehensive review details how three FDA-approved therapies have dramatically improved spinal muscular atrophy outcomes while highlighting persistent comorbidities and ...
Patient Tumors Grown From Stem Cells Become Living Test Beds for Duchenne Gene Editing
Researchers converted Duchenne patient stem-cell teratomas into humanized models in which both gene-corrected cell transplants and lipid nanoparticle base editing ...
Scientists Switch On an Embryonic Gene to Rescue a Lethal Blood Disorder
Oxford researchers have identified the DNA switches that silence the embryonic ζ-globin gene and shown that base editing them restores ...
Million-Dollar Cures: Why Insurance Policy Now Decides Which Children Get Gene Therapy
A new Pediatric Research commentary argues that insurance coverage and reimbursement policy, not the underlying science, now determine which children ...
CRISPR Multiplex Editing Emerges as a Master Key for Stress-Resilient Crops
A new review in Plant Cell Reports charts how CRISPR multiplex genome editing has become the definitive tool for mapping ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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