Tag: base editing

Researchers delivered an adenine base editor as a protein into human embryos, achieving efficient PCSK9 editing without double-strand breaks, though ...

Researchers at the University of Toronto engineered an ionizable lipid, LC-1, that preserves its fusogenic structure when loaded with large ...

Researchers transformed the inactive compact nuclease CgCas12n into a high-efficiency genome and base editor through arginine enrichment and guide RNA ...

A new review traces how CRISPR genome editing has evolved from blunt molecular scissors into increasingly precise therapeutic tools for ...

Researchers have shown that CRISPR base editors can correct three pathogenic Artemis mutations ex vivo with up to 50 percent ...

Kyoto University researchers used adenine base editing to correct the TFG mutation behind HMSN-P, delaying disease onset and extending survival ...

Researchers have fused HMGN1 and VP64 to a PAM-flexible, truncated-CDA1 base editor, boosting precision and efficiency for editing nearly any ...

Scientists have engineered densely chemically modified guide RNAs that boost prime editing efficiency in the mouse liver to nearly 70 ...