Researchers discover that the breast cancer drug fulvestrant promotes estrogen receptor DNA binding and active histone acetylation despite leaving chromatin ...
A time-course investigation shows how progressive chromatin remodeling and key regulatory factors direct human embryonic stem cells into kidney organoids.
A new study reveals that chromatin accessibility changes precede gene expression during the osteogenic differentiation of porcine synovium-derived mesenchymal stem ...
A genomic and transcriptomic reanalysis of Dictyostelium discoideum reveals that the amoeba relies on wobble decoding and early biosynthetic silencing ...
A multi-omics study shows that lactate produced by senescent breast cancer cells drives the SASP through histone H3 lactylation at ...
A computational reanalysis of public EBV data finds that promoters contacted by the viral EBER noncoding RNAs remain chromatin-accessible yet ...
An integrative ATAC-seq and RNA-seq study of induced endothelial cells from capillary malformation patients identifies inflammation-associated chromatin remodeling and distal ...
Genetic loss of CDH1 remodels human mammary epithelial cells toward a luminal progenitor-like state, modeling an early step in invasive ...
JuxtaBAM uses variants discovered within joint epigenomic and transcriptomic datasets to flag possible sample mismatches and duplications without requiring predefined ...
A single-nucleus multiome atlas of over 100,000 brain cells reveals disease-linked regulatory programs and potentially causal genetic variants in the ...
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