Mouse study links stress to shortened astrocyte cilia in amygdala
A mouse study found that chronic stress shortened primary cilia on amygdala astrocytes, while restoring the structures improved some stress-related ...
Tag: astrocytes
GFAP mutations selectively reshape lipids in Alexander disease cell model
A targeted lipidomic study in engineered human astrocytoma cells found that Alexander disease-associated GFAP mutations caused distinct, extensive changes in ...
Astrocyte Responses to Obesity May Disrupt Blood Pressure Control
A 2026 review proposes that reactive astrocytes in hypothalamic and brainstem circuits may contribute to obesity-associated hypertension through glutamate disruption, ...
Dynamic association of APLNR with astrocytic remodeling in the cuprizone-treated corpus callosum
A controlled mouse study found that APLNR was associated with region- and phase-dependent astrocytic responses during cuprizone-induced demyelination and partial ...
ABCA1 cholesterol trafficking implicated in Parkinson’s neurodegeneration in mice
Human postmortem tissue, cultured cells and mouse experiments implicated abnormal ABCA1-dependent cholesterol trafficking in Parkinson’s-related neurodegeneration.
Sugar Coats on Aging Brain Blood Vessels May Hold Clues to Late-Onset Epilepsy
A new review proposes that age-related remodeling of the sugar layer lining brain blood vessels could converge with galectin-3 inflammatory ...
Pomegranate Compound Ellagic Acid Calms Inflamed Brain Cells in Lab Study
Brazilian researchers found that ellagic acid, a polyphenol from pomegranates and berries, reduced oxidative stress and selectively rebalanced inflammatory signalling ...
How Stroke Injury Feeds the Brain’s Deadliest Tumors
A new Nature Cancer study shows that stroke remodels the brain's tumor microenvironment, creating tumor-associated astrocytes and macrophages that drive ...
Gene Found That Lets Transplanted Blood Stem Cells Rebuild the Brain’s Immune Defenses
Stanford researchers used a CRISPR screen in expanded blood stem cells to identify Elp1 as an essential regulator of myeloid ...
MSC-Derived Extracellular Vesicles May Reprogram the Inflamed Spinal Cord After Injury — But the Road to the Clinic Is Steep
A comprehensive review maps how MSC-derived extracellular vesicles modulate the inflammatory microenvironment after spinal cord injury across acute, subacute, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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