ZIF-8 Nanocarrier Delivers Plant Drug and Gold Nanorods to Attack Melanoma
Researchers have built a ZIF-8-based nanosystem loaded with conferone and gold nanorods that shows potent, targeted, pH-responsive activity against melanoma ...
Tag: apoptosis
Tiny RNA Cluster Revealed as Master Switch Behind Lung Cancer Survival and Immune Evasion
Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...
Vitamin D’s Active Form Triggers Cell Death and Rewires Purinergic Signaling in Melanoma Cells
A new study shows that calcitriol, the active form of vitamin D, kills A375 melanoma cells through mitochondrial dysfunction and ...
Copper Overload Pushes Cells Toward Death in Wilson Disease
A new review in Cell Death & Discovery links copper overload, mitochondrial failure and regulated cell death pathways including cuproptosis ...
Deleting a Potassium Channel Rewires How Glioblastoma Cells Respond to FLASH-Style Radiation
Deleting the BKCa potassium channel alters oxidative stress, DNA damage signaling and repair gene expression in glioblastoma cells exposed to ...
Common Anaesthetic Drugs Show Surprising Anti-Cancer Effects in Lab Study
An exploratory laboratory study finds that commonly used anaesthetic drugs such as ketamine, propofol and lidocaine can inhibit the growth, ...
Why Mature Human Sperm Resist TNF-α: The TNFR1 Apoptotic Shield Explained
New research shows that mature human spermatozoa resist TNF-α-induced apoptosis because their surface TNFR1 receptors cannot assemble the downstream signaling ...
Old Chemotherapy Drug Carmofur Shows New Power Against Aggressive Ovarian Cancer
A new study shows that the fluorouracil derivative carmofur kills aggressive ovarian cancer cells and blocks their migration by disrupting ...
Engineered Cytisine Derivative Disrupts Redox Balance to Kill Lung Cancer Cells
Researchers engineered a thiourea-bridged cytisine derivative, YU-C-ThioU-9, that overwhelms the antioxidant defenses of lung cancer cells by disrupting Nrf2-Keap1 and ...
New 5-FU Derivative EB-18 Shows Potency Against Resistant Cancers
Researchers have engineered EB-18, a phosphonium-substituted derivative of the classic chemotherapy drug 5-fluorouracil that outperforms 5-FU and standard agents in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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