Dementia Is Rare in Amazonian Indigenous Groups, but Survival Tells a Different Story
A longitudinal study of the Tsimané and Mosetén peoples of the Bolivian Amazon finds that dementia incidence is similar to ...
Tag: APOE4
ApoE4 May Raise Risk of Cognitive Decline From Small Vessel Disease, Review Finds
A new narrative review argues that ApoE4 acts as a context-dependent susceptibility modifier in cerebral small vessel disease rather than ...
Human Brain and Heart Tissue Models Head to Space Station to Probe Aging in Orbit
Mount Sinai researchers are launching bioengineered human brain and cardiovascular tissue models aboard the SpaceX CRS-35 mission to study microgravity, ...
Could Failing Myelin Flexibility Drive Cognitive Decline in Alzheimer’s Disease?
A new Perspective in PLOS Biology proposes that Alzheimer's disease may impair activity-dependent adaptive myelination by gray-matter oligodendrocytes, contributing to ...
Protective APOE2 Gene Softens the Damage Wrought by Alzheimer’s Risk Gene APOE4
New research in mice shows that the protective APOE2 allele actively counteracts amyloid plaque buildup, microglial dysfunction, and proteomic changes ...
AI Maps the Hidden Diversity of Amyloid Plaques Across the Alzheimer’s Brain
Using machine learning on tissue from 84 Alzheimer's disease cases, researchers have mapped six distinct amyloid-beta plaque types across 23 ...
APOE4 Splits Alzheimer’s Into Two Neurochemical Diseases, PET Imaging Study Reveals
A study of 387 amyloid-confirmed patients shows APOE4 carriers suffer cholinergic basal forebrain degeneration while non-carriers show dopaminergic loss, defining ...
Astrocyte Fibronectin Emerges as Key Driver of Blood–Brain Barrier Failure in Alzheimer’s Disease
A new Nature Aging study identifies astrocyte-derived fibronectin as the molecular link between the APOE ε4 allele, amyloid pathology, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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