Tag: antigen presentation

A 2026 narrative review links inherited HLA class I and class II variation to pediatric neuroblastoma susceptibility and selected outcomes, ...

A small clinical study linked lipid metabolism and mitochondrial respiration to low CD8-positive T-cell infiltration in esophageal adenocarcinoma using spatial ...

A phage-display and computational screen prioritized 14 Mycobacterium tuberculosis fragments as candidate HLA-E ligands, but experimental validation is still required.

An interpretable deep learning model called SPACER reads spatial transcriptomics data to reveal the molecular and spatial rules that govern ...

Mount Sinai researchers have received a five-year, $20.7 million agreement to develop the VITAL vaccine platform, beginning with an intranasal ...

A new study finds that calreticulin, long considered an essential chaperone for MHC class I antigen presentation, is functionally expendable ...

Single-cell multiomics reveals that people who progress from ACPA-positive at-risk status to clinical rheumatoid arthritis carry an expansion of senescent-like ...

Researchers at MD Anderson developed an AI tool called SPACER that decodes the spatial signals attracting or repelling immune cells ...

An interpretable machine learning framework called SPACER decodes the gene-level rules that recruit or exclude immune cells in tissues, revealing ...

A new review examines how trogocytosis, the process by which cells nibble membrane fragments from one another, shapes immune regulation, ...