Plant-Powered Hydrogel Halts Cell Death to Heal Diabetic Wounds
A bio-inspired hydrogel combining baicalein, glycyrrhizic acid nanofibers, gelatin and zinc ions suppresses ferroptosis in endothelial cells and closed 96 ...
Tag: angiogenesis
Cancer’s Hidden Helpers: Fibroblast Diversity Reshapes How Tumors Spread and How We Treat Them
A new review in Molecular Cancer maps the diverse states of cancer-associated fibroblasts and argues that precisely modulating, rather than ...
Hypoxia-Programmed Macrophage Vesicles Turn the Immune System Into a Bone-Healing Engine
Scientists engineered hypoxia-preconditioned macrophage vesicles that display apoptotic eat-me signals and, when delivered in a GelMA hydrogel, reprogram inflammation and ...
Progesterone Sensitizes Ovarian Cancer Cells to Paclitaxel by Reshaping Microtubule Chemistry
New laboratory research shows progesterone increases vasohibin-2 expression and tubulin detyrosination in progesterone receptor-negative ovarian cancer cells, sharply boosting their ...
Oncogenic viruses hijack a lysosomal receptor to fuel cancer growth
A new Nature Microbiology study shows that oncogenic viruses hijack chaperone-mediated autophagy by inducing TRIM32-mediated SUMOylation of LAMP2A, promoting viral ...
Smart Shrinking Hydrogel Fights Infection and Rebuilds Wounds With a Flash of Light
A light-triggered contractile hydrogel that releases antibiotics on demand and then promotes blood vessel growth closed nearly 98 percent of ...
Reprogrammed Stem Cells Show Promise for Healing Chronic Wounds That Refuse to Close
A comprehensive narrative review details how induced pluripotent stem cells, their extracellular vesicles, and engineered skin constructs are advancing chronic ...
Machine learning uncovers a novel phthalazine drug candidate against deadly brain tumours
Researchers used an explainable machine learning model built from 216 diverse VEGFR-2 inhibitors to discover a novel naphthalene-substituted phthalazine compound ...
Toad Venom Compound Bufalin Blocks Melanoma Growth by Switching Off AKT Signaling
New research shows that bufalin, a steroid from traditional Chinese toad venom, suppresses melanoma growth, metastasis and angiogenesis by reducing ...
Red Blood Cell Membranes Rewire Endothelial Metabolism to Spark New Vessel Growth
New research shows that membranes released when red blood cells lyse deliver an ATP-driven signal that metabolically reprograms endothelial cells ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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