Alzheimer

The amyloid precursor protein is processed differently by an alteration in their glycosylation that leads to increased production of beta amyloid, the trigger pathological effector for Alzheimer's disease Despite the important advances in…

The hour-long sessions will focus on different areas of brain research and feature expert speakers, with the goal of highlighting the HBP's scientific achievements and the state-of-the-art services offered by its new infrastructure for…

The prevalence of dementia in places where more than one language is spoken is 50% lower than in regions where the population uses only one language As well as allowing us to communicate with other people, languages are the tool we use to…

BOSTON - Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans. γ-Secretase…

Drug delivery technology is aimed at helping people with spinal cord and other nervous system disordersCredit: KiBum Lee, Letao Yang and Brian M. Conley A Rutgers-led team has created a smart drug delivery system that reduces…

Five-year-gift to Joseph Arboleda-Velasquez, MD, Ph.D., enables further investigation of potential genetic resistance to Alzheimer's as he works toward an ultimate goal of developing treatmentsCredit: Mass Eye and Ear Joseph F.…

Corresponding Author: Yasmin Hurd, PhD, Director of The Addiction Institute of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, and other coauthors. Bottom Line: Herion-addicted individuals have alterations in the…

Even without cognitive problems, those with Alzheimer's-related brain damage at increased risk of falls Falls are the leading cause of fatal injuries in older adults, causing more than 800,000 hospitalizations and about 30,000 deaths in…

Researchers seek to understand the biological framework of Alzheimer's disease in multi-ethnic populations and how it differs from that of non-Latino whites.Credit: HSC Researchers at HSC Fort Worth were awarded a grant expected to…

(Boston)--Since 1976, the Framingham Heart Study (FHS)--the longest running multi-generational epidemiological study in the world--has followed participants for incident dementia. The findings have helped to analyze the differences…

Credit: IU School of Medicine INDIANAPOLIS--Supported by a $1.3 million grant from the U.S. Administration for Community Living, Department of Health and Human Services, Indiana University School of Medicine and its partners have…

HABLE study prioritizes brain imaging and biomarker research among Mexican AmericansCredit: NIH/NIA To meet the pressing need to better understand the prevalence, progression, and clinical impact of Alzheimer's disease among…

Credit: Dan Addison | UVA Health UVA researchers have discovered that concussions and traumatic brain injuries, even when mild, cause swelling that blocks the brain's ability to clean itself of harmful toxins and debris.…

Four newly funded exploratory centers will bolster diversity: geographic, community and scientificCredit: NIH/National Institute on Aging To further incentivize innovative ideas and opportunities in Alzheimer's disease and related…

Results from a new study suggest that lifestyle changes may help to improve cognition in older adults experiencing cognitive decline that precedes dementia. In the study published in the Journal of the American Geriatrics Society, 119…

SLC25A51 gene encodes a protein that transports NAD+, a critical coenzyme in cellular metabolism, to mitochondria PHILADELPHIA -- Penn Medicine researchers have solved a decades old mystery around a key molecule fueling the power plant of…

Hypothesis describes the role of iron deposits in the brain as the cause of dementia in alcoholics (Vienna, 09 September 2020) A common consequence of chronically high alcohol consumption is a decline in cognitive function, which can even…

A new study reveals that reduced body temperature plays a major role in initiating the extensive health benefits of calorie-restricted diets. LA JOLLA, CA--Cutting calories significantly may not be an easy task for most, but it's tied to a…

Penn study finds that toxic proteins from mutated gene stimulate TDP-43 clumping, which can result in diseases like Lou Gehrig's disease PHILADELPHIA -- An investigational drug that targets an instigator of the TDP-43 protein, a well-known…

Microglia brain cells can be targeted with nanomedicines to tamp down uncontrolled inflammation activation, which causes neurodegenerative diseasesCredit: Nanxia Zhao WASHINGTON, September 8, 2020 -- Inspired by the need for new…