Tiny genetic switches: how microexons quietly rewire where proteins live in our cells
A new study shows that alternative splicing, especially through microexons shorter than five amino acids, fine-tunes protein interaction interfaces to ...
Tag: AlphaFold2
Symbiotic Bacteria Carry a Hidden Arsenal of Gene-Controlling Weapons, Structural Study Reveals
A structural analysis using AlphaFold2 reveals that symbiotic rhizobial effectors are modular proteins carrying hidden DNA- and RNA-binding domains, including ...
Wheat’s Greenbug Shield Traced to a Rare Kinase Fusion Protein
Researchers have cloned the wheat greenbug resistance gene Gb3 from Aegilops tauschii and shown it encodes an active kinase fused ...
AlphaFold Structures Turn Light-Sensitive Protein Variants Into Predictable Molecular Maps
Researchers have developed Foldinsight, a framework that uses AlphaFold2-predicted structures and molecular field descriptors to model and spatially interpret the ...
Hidden Blueprint in Aphid Proteins Shows How Evolution Can Rescue AI Structure Prediction
By sequencing closely related aphid species to supply missing evolutionary context, Stowers Institute researchers revealed a shared saposin-like structural blueprint ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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