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Recent Data Reveals Declining MMR Vaccination Rates Across the U.S.

June 2, 2025
in Medicine
Reading Time: 4 mins read
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County-level MMR vaccination rates pre-pandemic
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A newly released comprehensive dataset from researchers at Johns Hopkins University has revealed a concerning national decline in the measles-mumps-rubella (MMR) vaccination rates among children across counties in the United States since the onset of the COVID-19 pandemic. This research provides an unprecedented granular view at the county level, offering critical insights into vaccination trends that have significant public health implications. The analysis encompasses data from 2,066 counties, unveiling a widespread downturn in vaccination coverage that jeopardizes herd immunity against these highly contagious viral infections.

Prior to the pandemic, the average MMR vaccination rate at the county level stood at an already modest 93.92%. Post-pandemic data reflects a notable dip, with an average rate falling to 91.26%, marking a mean reduction of 2.67%. While seemingly small, this decline is epidemiologically significant, pushing many communities further away from the established 95% vaccination threshold required to sustain herd immunity against measles. The implications of slipping below this critical threshold risk a resurgence of outbreaks and loss of containment of viral transmission.

Of the 2,066 counties analyzed, a staggering 1,614—approximately 78%—reported decreases in the county-level vaccination rates. This widespread trend underscores the pandemic’s disruptive effect on routine childhood immunization programs. The altered healthcare access, resource reallocation to COVID-19 response, vaccine hesitancy exacerbated by misinformation, and interruptions to school-based vaccination campaigns likely contributed to this decline. Only a handful of states, including California, Connecticut, Maine, and New York, demonstrated a reversal with increases in median county vaccination rates, highlighting the considerable heterogeneity of vaccination dynamics across the nation.

This dataset, published in the highly regarded journal JAMA, coincides with an alarming rise in measles cases reported within the United States this year. Over one thousand instances have been confirmed, representing one of the highest annual case counts in more than thirty years, second only to the historically severe spike documented in 2019. Notably, the vast majority of these cases involve unvaccinated children, emphasizing the direct consequences of declining immunization coverage and underscoring the urgent need for targeted public health interventions.

Lauren Gardner, the senior author and director of Johns Hopkins University’s Center for Systems Science and Engineering, remarked on the critical importance of this dataset. Gardner, renowned for leading the data collection effort behind the globally utilized Johns Hopkins COVID-19 dashboard, highlighted the utility of high-resolution vaccination data to dissect complex epidemiological patterns. This granular information provides an essential tool for health authorities to predict measles transmission risk and to tailor vaccination strategies locally rather than relying on coarse state or national averages, which can mask underlying vulnerabilities.

The dataset expands upon existing state and national level statistics available from the Centers for Disease Control and Prevention (CDC), furnishing a more detailed landscape of MMR vaccination coverage variation. The evaluation reveals that vaccination patterns vary not only between states but also significantly within states, reflecting diverse socio-economic, cultural, and political factors influencing healthcare behaviors and access. Understanding these fine-scale disparities is crucial for designing precision public health approaches capable of arresting potential outbreaks before they escalate.

Researchers compiled two-dose MMR vaccination rates among kindergarteners by extracting data from individual state health department websites spanning from 2017 through 2024 where available. This extensive timeframe captures trends before, during, and after the COVID-19 pandemic. Overall, the dataset includes vaccination information from 2,237 counties across 38 states, rendering it one of the most comprehensive county-level vaccine coverage databases currently available in the United States.

This thorough documentation enables researchers and policymakers to monitor vaccination trends over time and spatially throughout the country. Equally, the data highlights the urgency to reverse declining vaccine uptake and to reinforce education and outreach programs to combat misinformation and vaccine hesitancy, which have intensified during the pandemic era. Strengthening public trust in vaccination programs is imperative to restore population immunity and to prevent future outbreaks of measles, mumps, and rubella, diseases that, although vaccine-preventable, can cause severe morbidity and mortality.

Continuous surveillance provided by this dataset empowers stakeholders to identify vulnerable counties exhibiting significant vaccination declines, enabling timely public health responses. Furthermore, such high-resolution data can inform mathematical models predicting the risk and spread of measles outbreaks, facilitating resource allocation targeted to high-risk communities. The data-driven approach advocated by Gardner’s team epitomizes a shift towards leveraging big data and advanced analytics in infectious disease control and prevention.

While the pandemic itself disrupted routine healthcare delivery and preventive measures, this dataset illustrates that the reprocussions extend beyond COVID-19, amplifying susceptibility to other infectious diseases with established prevention methods. The resurgence of measles cases paired with declining vaccination rates is a stark reminder that maintaining robust immunization systems is essential for safeguarding public health resilience, especially in the face of emerging global health challenges.

As measles remains one of the most transmissible human viruses, even slight reductions in vaccine coverage can precipitate outbreaks. The findings underscore the delicate balance of herd immunity and the consequences of perturbations within vaccination programs. The Johns Hopkins team’s research not only maps this landscape but also provides a transparent resource with open data available for download, encouraging collaborative efforts across academia, public health agencies, and policymakers to confront this emerging threat effectively.

The dataset authors include former adjunct assistant research scientist Ensheng Dong, graduate student Samee Saiyed, former research assistant Andreas Nearchou, undergraduate student Yamato Okura, and senior author Lauren Gardner, all affiliated with Johns Hopkins University. Their collective expertise in epidemiology, data science, and disease modeling fortifies the rigorous approach underpinning this pivotal contribution to infectious disease surveillance.

As public health communities digest these findings, there is a renewed call to action to bolster vaccination campaigns, enhance surveillance systems, and deploy innovative communication strategies aimed at increasing vaccine acceptance. Reinforcing and expanding routine immunizations amid the lingering challenges of the COVID-19 pandemic is critical to protecting the most vulnerable populations and restoring the United States’ hard-won gains against vaccine-preventable diseases.


Subject of Research: Decline in county-level MMR vaccination rates in the United States post-COVID-19 pandemic.

Article Title: Not specified in the content.

News Publication Date: Not specified beyond "published today" relative to dataset release.

Web References: None provided.

References: Data published in JAMA.

Image Credits: Johns Hopkins University.

Keywords: Viral infections, Preventive medicine

Tags: childhood vaccination trends U.S.granular county-level vaccination dataherd immunity challengesimpact of COVID-19 on immunizationJohns Hopkins University research findingsmeasles mumps rubella vaccine analysisMMR vaccination rates declineoutbreak risks from low vaccinationpublic health implications of vaccinationpublic health policy and vaccinationvaccination access disruptionsvaccination coverage reduction statistics
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