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Microglial deletion induces despair-like behavior associated with astrogliosis

July 29, 2026
in Psychology & Psychiatry
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Microglial deletion induces despair-like behavior associated with astrogliosis

Microglial deletion induces despair-like behavior associated with astrogliosis

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Wang, X., Liao, SH., Wang, N. et al. Microglial deletion induces despair-like behavior associated with astrogliosis.
Transl Psychiatry (2026). https://doi.org/10.1038/s41398-026-04325-7

https://doi.org/10.1038/s41398-026-04325-7

Tags: astrocyte activation and astrogliosiseffects of microglia depletion on brain functionglial cell interactions in neuropsychiatryimplications for depression treatment targeting glial cellsmicroglia and behavioral despairmicroglia role in neuroinflammationmicroglia-astrocyte crosstalkmicroglial deletion and depression-like behaviorneurobiological mechanisms of despair-like behaviorsneuroimmune interactions in psychiatric disordersneuroinflammation in depression models
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