Medicine
Remdesivir improves outcomes in adult kidney transplant recipients with COVID-19
Remdesivir may offer benefits that extend well beyond the initial days of COVID-19 in adults living with kidney transplants, according...
Methylglyoxal and acrolein disrupt arginine balance, causing hyperglycemia in male zebrafish
A new study in Nature Communications reports that two reactive metabolites—methylglyoxal and acrolein—can disrupt a key metabolic pathway in male...
Biguanide derivative 4C boosts talazoparib by triggering ferroptosis in bladder cancer
A new preclinical study reports that a previously underexplored biguanide-based compound, 4C, can dramatically enhance the anticancer effects of talazoparib...
Vitamin B3 therapy may reduce severity of rare genetic disease
Children born with NAXD deficiency—a genetic disorder that can be rapidly fatal—may have a better future with early, high-dose vitamin...
Link Between Weight Changes and Cognitive Decline in Older Adults
In an era where global populations are aging, cognitive decline has become a public-health priority. Yet the factors that shape...
Fractionated Proteomics Uncovers Protein Network Reducing Exercise-Induced Muscle Damage
Resistance training is celebrated for building strength, but it also triggers a cascade of molecular stress in skeletal muscle—damage that...
Standardizing Lung Ultrasound to Improve Neonatal Care Outcomes
A new study shines a spotlight on a simple but potentially transformative idea in neonatal intensive care: making lung ultrasound...
Alpha-synuclein Aggregates Differentially Alter Electrophysiology of SNpc and VTA Neurons
A team led by Del Popolo and colleagues reports that aggregated α-synuclein—an established driver of Parkinson’s disease pathology—does not affect...
Study finds higher healthcare costs linked to inappropriate medication use in seniors
A new matched-cohort study tracking older adults has quantified a problem clinicians often flag but rarely measure at scale: the...
Single-Plane Imaging Tracks Dynamic 3D Structures in Living Cells with Focus Feedback
A new protocol promises to make three-dimensional tracking in living cells far less punishing for both cells and microscopes. Instead...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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