Cancer
Triple-Drug Antibody-Drug Conjugate Strategy Shows Promise in Hard-to-Treat Breast Cancer
A real-world study of 87 patients suggests that combining Trop-2 antibody-drug conjugates with PD-1 inhibitors and anti-angiogenic therapy substantially improves...
Dogs May Not Respond to Thalidomide, Genetic Study Warns
Genomic analysis of nearly 2,000 dogs reveals that they carry the same cereblon variation that makes mice insensitive to thalidomide,...
Four-Gene Signature Tied to Young Age Predicts Breast Cancer Recurrence Risk
A new study identifies a four-gene expression signature linked to young age that independently predicts recurrence risk in breast cancer.
Radiation or Surgery After Dual Immunotherapy Fails to Extend Survival in Metastatic Lung Cancer
The Phase III LONESTAR trial found that adding radiation or surgery after nivolumab plus ipilimumab did not improve survival in...
Tumor Size Emerges as Key Prognostic Factor in FIGO 2018 Stage IIIC Cervical Cancer
A retrospective Turkish study of 144 cervical cancer patients finds that tumor size independently predicts survival within the heterogeneous FIGO...
Flavonoid Diosmetin Targets Endothelial Enzyme to Rewire Lung Cancer Immune Defenses
New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses...
Dark DNA’s Long RNAs Emerge as Master Regulators of Colorectal Cancer
A major new review shows that long non-coding RNAs orchestrate the colorectal cancer tumour microenvironment, offering new biomarkers and therapeutic...
Neutrophils in Cancer: The Immune Cells That Turn Traitors and Healers
A comprehensive new review reveals how neutrophils, the immune system's most abundant white blood cells, are co-opted by tumors to...
Bile Acids Emerge as Master Regulators Linking Gut Microbes, Immunity and Cancer
A new commentary in Holistic Integrative Oncology argues that bile acids act as master signaling molecules linking liver metabolism, gut...
Tumor Vesicles Loaded with SPP1 Rewire Fibroblasts to Shield Lung Cancer from Immunity
New research shows that lung adenocarcinoma cells package the protein SPP1 into extracellular vesicles to reprogram fibroblasts into an MMP11-positive...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!