Cancer
Two-Pronged Immunotherapy Strategy Cracks Glioblastoma’s Defenses in Preclinical Study
Wistar Institute scientists report that combining the kidney cancer drug axitinib with a 4-1BB agonist overcame myeloid cell suppression and...
Tiny Vesicles, Big Problem: How Exosomes Drive Cancer Immunotherapy Resistance
A new review in Molecular Cancer explains how tumor-derived exosomes act as mobile signaling hubs that spread immune suppression, drive...
Blood Test Tracks Tumour Oxygen Starvation and Predicts Radiotherapy Benefit in Bladder Cancer
A nanoparticle-enabled blood proteomics test can measure tumour hypoxia in bladder cancer patients, track it during radiotherapy and predict who...
Real-World Data Show Carfilzomib Regimens Deliver Strong Results in Multiple Myeloma
The final results of the German CARO study show that carfilzomib-based regimens achieve high adherence, trial-consistent effectiveness, and stable quality...
Gut Microbes Emerge as Hidden Drivers of Diabetes and Pancreatic Cancer
A new review in Medical Oncology argues that gut microbial dysbiosis drives systemic inflammation that contributes to both type 2...
How Shapeshifting Tumor Cells Outsmart Cancer Treatment
A new review explains how tumor cells reversibly switch identities through epigenetic and microenvironmental programs, driving metastasis and therapy resistance.
Under the Microscope: Tumor Invasion Grading Predicts Survival After Liver Cancer Conversion Therapy
A multicenter study shows that grading the severity of microvascular invasion in resected liver tumors strongly predicts recurrence and survival...
Text Message Screening Catches Nerve Damage in Chemotherapy Patients
A Sydney study shows that brief patient-reported questionnaires delivered by automated text messages can feasibly screen chemotherapy patients for peripheral...
Age, Frailty and Function Predict Who Survives Brain Metastasis Surgery
A bicentric study of 132 patients finds that advanced age, poor functional status, frailty and lack of adjuvant treatment sharply...
Not All Collapsed Lungs Are Equal: Why AI Must Catch the Neonatal Pneumothoraces That Matter Most
A new Matters Arising exchange in Pediatric Radiology argues that overall accuracy is the wrong benchmark for AI systems detecting...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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