Cancer
Hidden Genetic Fault Lines Reshape Gastric Cancer Treatment Maps in Landmark Chinese Cohort
A 563-patient genomic study from Peking University reveals how KMT2C/D loss-of-function alterations define a hypermutated, MSI-high subgroup of gastric cancer...
RNA-Binding RBM Proteins Emerge as Double-Edged Players in Cancer
A new review in Medical Oncology details how the RBM family of RNA-binding proteins acts as both tumor suppressors and...
Hidden Immune Saboteurs: Scientists Map the Cells That Shield Colorectal Tumors
By combining spatial and single-cell transcriptomics, researchers have mapped previously unknown immunosuppressive niches in colorectal cancer, including SPP1-positive macrophage rings...
Fewer Than One in Ten Lynch Syndrome Patients Use Aspirin to Prevent Colorectal Cancer
A German survey of 539 people with Lynch syndrome found that despite strong evidence that daily aspirin reduces colorectal cancer...
Exercise Gap: Most Men With Advanced Prostate Cancer Walk Enough, but Few Lift Weights
A large international registry study finds that while 58 to 63 percent of men with advanced prostate cancer meet aerobic...
Insulin Receptor Signaling Is Not One Pathway: Engineered Mimetics Reveal a Programmable Network
A new review argues that insulin receptor signaling is a programmable, context-dependent network that engineered mimetics can selectively retune across...
Anemia Strikes Two-Thirds of Late-Stage Cancer Patients, Yet Most Go Untreated
A multicenter study of 1,546 advanced cancer patients in Beijing found that 65.1 percent developed anemia during third-line or later...
Immune Receptor LAIR1 Blocks Cancer Cell Engulfment in Brain Tumours
New research in the British Journal of Cancer shows that the collagen-binding receptor LAIR1 disables the phagocytic machinery of glioma-associated...
Iron and Copper Cell Death Pathways May Hold Key to Beating Immunotherapy Resistance
A new review in Medical Oncology argues that simultaneously inducing the iron-driven cell death ferroptosis and the copper-driven cuproptosis, tuned...
Cancer’s Hidden Proteome: Thousands of Dark Proteins Emerge as Drug Targets
A landmark Perspective in Nature Reviews Cancer argues that the cancer dark proteome — thousands of uncharacterized proteins from non-canonical...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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