Biology
Peyer’s patch M cells sustain epithelial group 3 innate lymphoid cells, IL-22
Peyer’s patches, the immune outposts embedded in the lining of the small intestine, may be more than passive sentinels waiting...
REDCAT Enables All-Optical Multimodal Mapping of Metabolism in Specific Cell Types
A new research paper introduces a method for watching metabolism at the level of individual cell types without relying on...
Universal Pipeline Enables High-Resolution GPCR Structure Determination
G protein-coupled receptors, or GPCRs, sit at the crossroads of biology and medicine. Embedded in cell membranes, these molecular sensors...
Targeting METTL3/m6A/SOCS3 Reprograms Macrophages, Boosting Anti-PD-1 Therapy in Multiple Myeloma
Multiple myeloma may be vulnerable to an unexpected form of immune-system engineering: changing the behavior of the macrophages that surround...
Genomes reveal how Sotalia dolphins diverged while retaining key conserved traits
A new genomic study of South America’s Sotalia dolphins has revealed how two closely related species began diverging after one...
CHAMS-DTA Improves Drug-Target Binding Affinity Prediction with Cross-Hybrid Attention and Multistage Sampling
Drug discovery is getting a new computational assist from an artificial-intelligence model designed to predict how tightly a drug molecule...
Indian Polistine Wasps Harbor Distinct Microbiota Across Four Species
Wasps are often portrayed as solitary villains of the picnic table, but inside their bodies they host complex microbial communities...
Combining noncoding RNA profiles and HPV genotyping improves cervical cancer risk assessment
A new molecular screening strategy could help doctors distinguish human papillomavirus infections that are likely to disappear from those that...
Machine learning reveals HLA-DQ2.5’s impact on naïve T-cell receptors in celiac disease
A person’s immune system carries a molecular record of both genetic inheritance and past encounters with the outside world. That...
Scientists develop reporter strain to detect inhibition of bacterial cell-wall biosynthesis
A new bacterial “alarm system” could make it dramatically easier to discover antibiotics that attack one of microbes’ most vulnerable...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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