Biology
How Cells Build Their Protein Shredder: New Rules of Proteasome Biogenesis
A new review argues that mammalian cells regulate the construction of their proteasomes through layered transcriptional networks and assembly pathways,...
How Malaria Parasites Punch Through Cells to Spark Protective Immunity
New research shows that the damage malaria sporozoites inflict while punching through host cells, sensed via a wounding response requiring...
Inside a Moon-Mars Mock Habitat, Scientists Map the Hidden Living Microbiome
A multi-omics study of a 21-day mock Moon-Mars habitat mission reveals a resilient, spatially organized living microbiome dominated by Pseudomonas,...
Plant Viruses Already Carry Weapons That Can Blind CRISPR-Cas13
Plant viral suppressors of RNA interference HcPro and P19 unexpectedly block both Cas13-independent and Cas13-mediated transcript silencing, revealing that viruses...
Cell Cycle Breakdown Drives Sudden Bursts of Aneuploidy in Yeast Genomes
Experiments in hundreds of diploid yeast strains show that double losses of heterozygosity arise mainly from transient bursts of whole-chromosome...
WIND1 Rewrites Plant Cell Fate by Flipping a Single Histone Switch Both Ways
A new commentary highlights how the transcription factor WIND1 simultaneously promotes acetylation and deacetylation of histone H3 lysine 27, coordinating...
Space Radiation Leaves Distinct Mutational Fingerprints in Mouse Liver Tumors
Whole genome sequencing of liver tumors in outbred mice reveals distinct mutational fingerprints of heavy-ion and gamma-ray radiation, including frequent...
Gut Microbiome and Brain Chemistry Linked in Overlapping Reflux and Bowel Syndrome
A multi-omics study of patients with diarrhea-predominant irritable bowel syndrome and nonerosive reflux disease reveals gut dysbiosis, disrupted serotonin metabolism,...
Camera Traps Reveal Hidden Shifts in Tropical Fruit-Eating Wildlife as Forest Disturbance Rises
A camera trap study in French Guiana shows that fruit-eating vertebrate communities keep their species richness under disturbance but undergo...
Rosemary and Hibiscus Compounds Show Antibiotic-Strength Punch Against Deadly Bacteria
New research from India shows that bioactive compounds in rosemary and hibiscus extracts bind essential bacterial proteins with affinities rivaling...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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