Medicine
Blocking cyclin D1–CDK6 curbs inflammatory senescence genes and age-related functional decline
A familiar cell-cycle protein may be helping aging cells broadcast inflammatory signals throughout the body, according to a new study...
Spatial transcriptomics reveals dynamic cellular programs driving human heart transplant rejection
A heart transplant can restore circulation, reverse advanced heart failure and give patients years of life, but the new organ...
Sustained Extreme Heat Linked to Mental Health Hospitalizations Across Multiple Countries
A new multinational study has found that sustained extreme heat is associated with a measurable rise in hospitalizations for mental...
JP1 Peptide Modulates Oxidative Stress and Autophagy Through Keap1-Nrf2-ARE in ALS Mice
A small peptide derived from a stress-response protein has improved motor performance and extended survival in mice modeling amyotrophic lateral...
Dietary Calcium Linked to Hyperuricemia Among Chinese Adults, Survey Finds
A large analysis of Chinese adults has uncovered a potentially important—and unexpected—link between dietary calcium intake and hyperuricemia, the condition...
Real-world study finds direct bictegravir switch effective after first-line HIV treatment failure
Treatment failure on a first-line HIV regimen can mark a critical turning point in long-term care, raising questions about drug...
Study Finds Dietary Choices Differ From Validated Measures in Heart Disease Research
A new meta-research study is drawing attention to a largely invisible problem in nutrition science: the dietary exposure that researchers...
Multiplex PCR-Guided Antibiotics Tested in Ventilated Patients With Suspected Hospital-Acquired Pneumonia
Ventilator-associated pneumonia and hospital-acquired pneumonia remain among the most difficult infections to diagnose and treat in intensive-care medicine. Patients who...
Mapping Timing and Thresholds of Cerebrospinal Fluid Protein Changes in Guillain–Barré Syndrome
Guillain–Barré syndrome, or GBS, is one of the most urgent neurological disorders in which the body’s immune system attacks the...
Dartmouth researchers uncover risks in tick-borne alpha-gal syndrome beyond meat allergy
Lebanon, New Hampshire—A large international study led by researchers at Dartmouth Health and the Geisel School of Medicine at Dartmouth...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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