Cancer
Itaconate-treated macrophage exosomes boost breast cancer cell invasion in vitro
In vitro experiments found that exosomes from dimethyl-itaconate-treated macrophages increased EMT-associated changes, migration, and invasion in MCF-7 breast cancer cells...
Qualitative study maps uneven spiritual coping among cancer patients
A phenomenological study of 13 cancer patients found that spirituality offered meaning, hope and endurance for some participants but did...
CAIX PET/CT detects 97.9% of clear-cell kidney cancer lesions in prospective study
A prospective multicentre study found that CAIX-targeted Ga-DPI-4452 PET/CT detected 97.9% of clear cell renal cell carcinoma lesions, compared with...
Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic review
The analysis included seven eligible publications with a combined total of 262 patients and evaluated oral fluoropyrimidines used with cetuximab...
IL1RAP associated with aggressive features in papillary thyroid carcinoma
IL1RAP was associated with aggressive features in papillary thyroid carcinoma, while cell experiments linked its expression to proliferation, invasion, EMT-like...
Lab study links neurokinin receptor blockers to reduced breast cancer cell viability
Laboratory, computational and human tissue analyses suggest that neurokinin receptor antagonists reduce breast cancer cell viability and suppress invasion-related pathways,...
Liquid biopsy identifies tumor-derived mir-302/367 cluster as a macrophage-reprogramming axis sustaining immune cold prostate cancer
A prostate-cancer study found that extracellular vesicles carrying miR-302/367 microRNAs can reprogram macrophages toward an M2-like immunoregulatory state.
Survival remains limited in older transplant-ineligible mantle cell lymphoma
A population-based Ontario study found limited survival among older mantle cell lymphoma patients ineligible for autologous stem cell transplantation, with...
Machine learning links immune-cell measures to resected lung cancer prognosis
A retrospective study of 165 surgically treated patients found that machine-learning analysis of whole-slide images linked CD8-positive immune-cell density, Foxp3-positive...
18 new bacterial species recovered from prostate cancer sequencing data
A University of East Anglia-led analysis recovered 249 near-complete bacterial genomes from prostate cancer sequencing data, including 18 species not...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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