New research shows that the BTK inhibitor ibrutinib activates the protease matriptase in malignant B cells, preserving surface CD19 and...

New research shows that activating bystander T cells inside tumors triggers antigen-independent tumor killing through cytokines, nitric oxide and innate...

New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses...

A major new review shows that long non-coding RNAs orchestrate the colorectal cancer tumour microenvironment, offering new biomarkers and therapeutic...

A comprehensive new review reveals how neutrophils, the immune system's most abundant white blood cells, are co-opted by tumors to...

A new commentary in Holistic Integrative Oncology argues that bile acids act as master signaling molecules linking liver metabolism, gut...

New research shows that lung adenocarcinoma cells package the protein SPP1 into extracellular vesicles to reprogram fibroblasts into an MMP11-positive...

Researchers have built a machine learning framework that predicts context-specific synthetic lethal vulnerabilities between paralog gene pairs across 1,005 cancer...

New research shows that removing protein kinase C delta reprograms macrophage metabolism to suppress inflammatory pyroptotic cell death and stabilize...

A prospective imaging study shows that radium-223 significantly reduces PD-L1 expression and depletes immune cells in prostate cancer bone metastases,...