Early-Onset Cancers Are Rising Across the Nordic Countries, Landmark 20-Year Study Finds
A comprehensive analysis of Nordic cancer registry data from 2003 to 2022 shows incidence rates rising for 12 of 18...
Hidden RNA Switch Helps Esophageal Cancer Evade Ferroptotic Cell Death
A new study reveals that the m6A-stabilized long non-coding RNA SSTR5-AS1 helps esophageal cancer cells resist ferroptosis by recruiting FAM120A...
Six Months of Chemotherapy Before Surgery Matches Four-Month Course in Pancreatic Cancer
The PACT-21/CASSANDRA phase 3 trial found that six months of preoperative chemotherapy produced event-free survival comparable to a four-month preoperative...
AI Scours 1.2 Million Natural Products to Find Fungal Compound That Starves Glioblastoma of Cholesterol
An AI-driven screening pipeline identified the fungal sterol 5,6-epoxyergosterol as a selective LXRβ agonist that exploits the cholesterol dependency of...
Four-Gene Signature Tied to Young Age Predicts Breast Cancer Recurrence Risk
A new study identifies a four-gene expression signature linked to young age that independently predicts recurrence risk in breast cancer.
Radiation or Surgery After Dual Immunotherapy Fails to Extend Survival in Metastatic Lung Cancer
The Phase III LONESTAR trial found that adding radiation or surgery after nivolumab plus ipilimumab did not improve survival in...
Tumor Size Emerges as Key Prognostic Factor in FIGO 2018 Stage IIIC Cervical Cancer
A retrospective Turkish study of 144 cervical cancer patients finds that tumor size independently predicts survival within the heterogeneous FIGO...
Ibrutinib Triggers Matriptase to Preserve CD19 and Block Antigen Escape in B-Cell Malignancy
New research shows that the BTK inhibitor ibrutinib activates the protease matriptase in malignant B cells, preserving surface CD19 and...
T Cells Can Wipe Out Tumors Without Ever Recognizing Them
New research shows that activating bystander T cells inside tumors triggers antigen-independent tumor killing through cytokines, nitric oxide and innate...
Flavonoid Diosmetin Targets Endothelial Enzyme to Rewire Lung Cancer Immune Defenses
New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!