A new cross-platform review of eighteen FDA-approved RNA therapeutics finds that adverse effects depend more on delivery chemistry and administration...

A pilot study shows a needle-free blood collection device can sustain nine venous samples per visit through a single IV...

Korea University researchers used benchmarked AI models to design small-molecule fragments that experimentally inhibited the human enzyme DHPS, a host...

In vitro experiments show juglone, a naphthoquinone from walnut green husks, potently and competitively inhibits the human drug-metabolizing enzyme CYP2C9,...

Researchers developed ebastine-loaded Solusome nanovesicle oral lyophilisates that disintegrate in seconds and raised the drug's oral bioavailability 3.21-fold in rats.

A cross-sectional study of 363 final-year pharmacy and nursing students in Vietnam found that more than half self-medicated within six...

The nomination of ISM9546 arrives at a moment when the field of targeted protein degradation is moving well beyond its...

Tautomerism occupies a curious position in chemistry: it is conceptually simple, involving nothing more than the relocation of a single...

A new review maps how artificial intelligence is transforming RNA-targeted drug discovery across both small molecules and oligonucleotide therapeutics.

When a new medicine reaches the market, the work of protecting patients is only beginning. Before approval, clinical trials demonstrate...