HIV can dodge preventive antibody VRC01 after infection, trial sequencing reveals
Deep sequencing of breakthrough infections from the AMP trials shows that prophylactic VRC01 selected for low-frequency HIV escape mutations in...
Fatty Liver Cells Turn On a Caspase-2 Death Pathway That Damps Hepatitis B Replication
New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic pathway that is associated with reduced...
Fish-Specific Ubiquitin Ligase NHRE3 Helps Virus Evade Antiviral Defenses by Degrading ISG15
Researchers identified a fish-specific E3 ubiquitin ligase, NHRE3, that suppresses antiviral immunity in grass carp and rare minnows by tagging...
Half a Million Animal Bites Reveal Gaps in Iran’s Rabies Defense
A nationwide analysis of over 507,000 animal bite records in Iran reveals strong early initiation of rabies post-exposure prophylaxis but...
Machine Learning Reconstructs Missing Infection Links in COVID-19 Networks
Researchers in Cyprus used classical machine learning and GraphSAGE-based graph representation learning to predict missing transmission links in COVID-19 infection...
Better Pay and Sick Leave Could Curb COVID-19 in Nursing Homes, Model Finds
An agent-based simulation of 110 skilled nursing facilities in Missouri shows that paid sick leave and full-time staffing policies reduce...
Gut Protein Claudin-2 Revealed as a Hidden Defender Against Dangerous E. coli Infections
New research in Nature Communications shows that the tight-junction protein claudin-2 protects mice from Citrobacter rodentium infection and colitis by...
Malaria Parasites Must Burrow Through Cells to Spark Vaccine Protection, Study Finds
New research shows that the ability of malaria sporozoites to migrate through host cells before liver infection is a dominant...
Superbugs Lurk in Shared Waters of Kenya’s Maasai Mara, Yearlong Study Finds
A yearlong study of 28 shared waterpoints in Kenya's Maasai Mara Ecosystem found that every E. coli isolate was antibiotic-resistant,...
Gut Fat Molecules Steer a Worm’s Immune Defenses and Its Urge to Flee Pathogens
A new study in PLOS Biology shows that the nuclear hormone receptor NHR-68 links intestinal linoleic acid metabolism to both...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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