Gut Barriers and Maternal Antibodies Explain Patchy Rotavirus Vaccine Success
A new review explains why oral rotavirus vaccines protect children far less effectively in low- and middle-income countries, citing maternal...
mRNA Vaccines Deliver Lasting Protection Against Tapeworm Disease
New EG95-based mRNA-lipid nanoparticle vaccines induced stronger and longer-lasting immunity against cystic echinococcosis than conventional subunit vaccines in mice and...
Fast or Accurate? Modeling Reveals When Rapid Tests Beat PCR in Outbreak Control
A mathematical modeling study finds that rapid, less accurate tests can outperform slower PCR-style testing during outbreaks, but only when...
H5N1 Variants From a Severe Human Case Show Weakened Grip on Host Receptors
Cryo-EM and binding assays reveal that hemagglutinin mutations E190D and Q226H in H5N1 viruses from a severely ill British Columbia...
How Exercise Trains the Immune System to Fight Infection
New research in PLOS Pathogens reveals that exercise drives a protective metabolite pathway that pushes the NLRP3 inflammasome into a...
Heat Erodes Wolbachia Shield Against Dengue in Mosquitoes, Study Finds
A Vietnamese laboratory study using blood from dengue patients shows that rearing wMel-infected Aedes aegypti at higher temperatures reduces Wolbachia...
Sleeping Sickness Parasite Invades the Uterus and Disrupts Reproductive Hormones
A new study in PLOS Pathogens shows that Trypanosoma brucei invades the uterine lining, remodels the reproductive immune environment, and...
Antibody Survey Reveals Widespread Flavi- and Paramyxoviruses Circulating in African Fruit Bats
A large antibody-based survey across seven African countries finds high seroprevalence of flavi- and paramyxoviruses in fruit bats, linking large...
When Cultures Come Back Negative: Joint Infection Outcomes Are Better Than Feared
A systematic review of 27 studies and nearly 1,400 patients finds that culture-negative periprosthetic joint infection can achieve favorable outcomes,...
Blood Donors in Niger Reveal Vast Hidden Spread of SARS-CoV-2
A serosurvey of 3,656 blood donors in Niamey found SARS-CoV-2 antibodies in over half of unvaccinated participants, revealing extensive undetected...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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