IGF-I Gene Therapy Reshapes the Proteome of Cartilage-Forming Stem Cells from Osteoarthritis Patients
A new proteomic study maps how rAAV-mediated IGF-I gene transfer alters protein expression in bone marrow stromal cells from osteoarthritis...
High-Yielding Dairy Cows Carry More Resistance and Virulence Genes in the Rumen
Metagenomic sequencing shows long-lived high-yielding dairy cows carry more enriched antibiotic resistance, biocide and metal resistance, and virulence genes in...
Declining fertility rates may reshape future hereditary angioedema case numbers
A new correspondence explores how falling total fertility rates and disease-specific factors may reduce future new cases of hereditary angioedema.
Novel Pig Gut Spirochete Brachyspira burroughii Identified During Swine Dysentery Surveillance
Genomic and phenotypic analyses of weakly hemolytic isolates from two pig farms revealed a previously unrecognized Brachyspira species, now named...
GnRH Triggers a Transient Inflammatory-Like Response in Pituitary Cells During Ovulation
A new study shows that the preovulatory GnRH surge induces a transient inflammatory-like response and SAT1 upregulation in pituitary gonadotrope...
Walnut Oil Buildup Traced to Rising Enzyme Activity and Coordinated Gene Expression
A study of the walnut cultivar 'Wen185' links S-shaped oil accumulation during kernel development to rising ACCase, FAS, and AAT...
Research report: Transcriptome datasets of four freshwater bacterial isolates grown under iron-replete and iron-limited conditions
An open RNA-seq dataset from four freshwater bacterial isolates grown with and without iron documents 349,853,404 processed reads for comparative...
Whole-Genome Sequencing Explores Why Low-Risk Patients Develop Bleomycin Lung Injury
Whole-genome sequencing of 21 predominantly low-risk patients with bleomycin-induced pneumonitis identified biologically plausible candidate variants but no single unifying genetic...
Oxidative Stress Gene Signature Flags Prostate Cancer Recurrence Risk
A LASSO-based risk score built from oxidative stress-related genes predicts biochemical recurrence in prostate cancer, with LAMP5 knockdown reducing PC3...
Licorice Compound Glycyrrhizic Acid Curbs BVDV in Cells and Mice
Glycyrrhizic acid from licorice root suppressed BVDV replication by more than 80 percent in cell culture and reduced liver damage...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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