Habitat Maps Predict Genetic Health of an Endangered Toad
A new study in Heredity shows that carefully calibrated species distribution models can predict genome-wide genetic diversity and gene flow...
Scientists Identify Two Genes That Could Transform Heart Attack Diagnosis
Researchers combined bioinformatics screening with mouse experiments to identify PLAUR and IL1B as hub genes of hypoxia and ischemia in...
Folded DNA Structures in the Hepatitis B Genome Steer Viral Gene Expression
New research shows that conserved G-quadruplex structures in the hepatitis B virus genome recruit host proteins HNF4A and CNBP to...
Base Gap Switches Emerge as Programmable Regulators and DNA Biosensors
Researchers report that base gap switches, DNA devices engineered with a strategic missing base, act as programmable transcriptional regulators and...
Scientists Ramp Up Licorice Sweetener Glycyrrhizin With Elicitation and CRISPR
A new review details how elicitation, genome editing and engineered yeast are being used to boost production of the medicinally...
Chemical Tags on Messenger RNA Steer the Plasticity of Pancreatic Alpha Cells
A new Nature Metabolism study shows that m6A methylation of messenger RNA actively controls the plasticity of pancreatic alpha cells,...
New Tool Treats Genetic Ancestry as a Continuum to Sharpen Disease Risk Prediction for All Populations
A new method called SPLENDID models genetic ancestry as a continuum rather than discrete labels, significantly improving polygenic risk score...
Hidden RNA Switches Offer a New Way to Boost Genes in Rare Disease
Scientists have shown that removing hidden repressive elements from RNA messages with splice-switching antisense oligonucleotides can boost protein production from...
Epigenetic Marks and Jumping Genes Decide Which Parental Genome Rules Mustard
New research shows that asymmetric DNA methylation, histone marks and transposable element insertions explain why one parental genome dominates gene...
Lysosomal Fission Gene MROH1 Governs Thyroid Hormone Levels in Mice
Mice lacking the HEAT repeat protein MROH1 develop mild hypothyroidism and thyroid remodelling, linking a conserved lysosomal scission factor to...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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