A SHERLOCK-based CRISPR diagnostic platform called HOMEBRED achieves PCR-level sensitivity for pathogens and cancer biomarkers without laboratory equipment.

A new Gene Therapy article synthesizes evidence on how patients, consumers and societies value, perceive and prefer high-cost gene therapies...

A new Perspective in Nature Reviews Gastroenterology & Hepatology proposes an exposome-based framework to prevent inflammatory bowel disease through targeted...

A six-gene-edited pig liver transplanted into a brain-dead human recipient produced albumin and bile for 11 days, revealing both the...

A stage-resolved transcriptome atlas of rice flag leaves reveals two waves of gene reprogramming during grain filling that coordinate defense...

A genome-scale analysis of Orientia tsutsugamushi reveals that single-gene markers poorly reflect whole-genome evolution and that the bacterium possesses an...

A twenty-one-year genomic study of a commercial sugar beet breeding program reveals that three-way hybrid breeding has driven strong differentiation...

Researchers engineered an attenuated Pseudomonas aeruginosa strain to inject functional Cre recombinase into mouse lung cell nuclei, triggering gene recombination...

New research shows that the mRNA modification m6A, installed by METTL14, is required to maintain pancreatic alpha-cell identity and prevent...

A trio-based whole-exome sequencing study of Rwandan children with autism has identified rare pathogenic and uncertain variants in nearly a...