A new study maps how GSK-3β overexpression selectively alters dendritic spines and excitatory innervation across the hippocampal trisynaptic circuit, with...

A comprehensive review shows that miniaturized biosensor platforms can detect Alzheimer's, Parkinson's, and prion disease biomarkers at extraordinary sensitivity, but...

A real-world study of 77 advanced Parkinson's patients finds that neuropsychiatric side effects of foslevodopa/foscarbidopa infusion occur more often than...

A new review finds that induced pluripotent stem cells have transformed drug discovery for Alzheimer's disease, diabetes, arthritis and cancer...

Researchers used dansylated urinary metabolomics to reveal a distinctive amine and phenol chemical signature of Parkinson's disease and identify candidate...

A new computational study in Heliyon used pharmacophore modeling of marine-derived compounds to design synthetic gamma-secretase modulators that outperformed a...

Two new studies show that the Batten disease protein CLN8 catalyzes a key step in a non-canonical phospholipid synthesis pathway...

A narrative review of 119 studies finds that Alzheimer's disease biomarkers, including amyloid-beta, tau and neurofilament light chain, are consistently...

A French study finds colonic LRRK2 expression is strongly increased in Crohn's disease but not elevated in Parkinson's disease or...

New research in npj Parkinson's Disease shows that fatty acid nitroalkenes can inhibit LRRK2 kinase hyperactivation and provide neuroprotection in...