For people living with Parkinson's disease, the slow erosion of everyday movement is one of the disease's quiet cruelties. Even...

Researchers found that reducing SLITRK2 levels in human stem cell-derived FUS-ALS motor neurons restores axonal health and neuromuscular junction signaling,...

A large OCT study found generalized retinal layer thickening in patients with Steinert disease, including significant thickening of the retinal...

New research reveals how the gap junction protein connexin 36 is degraded in photoreceptor cells under excitotoxic stress, implicating autophagic,...

A new perspective in npj Parkinson's Disease proposes a six-dimensional MRI-based framework for capturing the biological heterogeneity of Parkinson's disease...

New research shows that environmental neurotoxicants damage mitochondria in ways that break down the nuclear pore complex and disrupt nucleocytoplasmic...

A computational screen of 2,847 plant compounds against ten Alzheimer's-related proteins identified 36 multitarget phytochemicals with stable binding and literature-backed...

Researchers used cationic liposomal delivery to introduce functional antibodies into living neurons, revealing that a phosphorylated tau form associated with...

Prion diseases are among the rarest and most uniformly fatal neurodegenerative disorders known to medicine. Conditions such as Creutzfeldt-Jakob disease,...

For decades, coffee has been one of the most tantalizing suspects in Parkinson's disease research. Population studies repeatedly suggested that...