Adipose triglyceride lipase driven lipolysis as a targetable metabolic vulnerability in prostate cancer with intrinsic metabolic inflexibility

Subject of Research: Cancer

Article Title: Adipose triglyceride lipase driven lipolysis as a targetable metabolic vulnerability in prostate cancer with intrinsic metabolic inflexibility

Article References: Tiefenbacher, A., Gudenus, M., Valcanover, D., Neudert, B., Sheibani-Tezerji, R., Mendrina, T., Kalla, J., Pajed, L., Draganić, K., Haitel, A., Haase, A., Hartenbach, M., Rasul, S., Berger, W., Breinbauer, R., Grabner, G., Schweiger, M., Compérat, E., & Egger, G. (2026). Adipose triglyceride lipase driven lipolysis as a targetable metabolic vulnerability in prostate cancer with intrinsic metabolic inflexibility. British Journal of Cancer. https://doi.org/10.1038/s41416-026-03545-4

Image Credits: AI Generated

DOI: 10.1038/s41416-026-03545-4

Keywords: adipose triglyceride lipase in prostate cancer, cancer cell energy metabolism, cancer metabolism and lipid pathways, intrinsic metabolic inflexibility in tumors, lipid metabolism in oncology, lipolysis targeting in cancer therapy, metabolic reprogramming in prostate cancer, metabolic vulnerability in cancer cells, novel metabolic vulnerabilities in prostate cancer, prostate cancer metabolic inflexibility, therapeutic targeting of lipolysis, triglyceride breakdown in cancer