New Horizons: ISTA Secures Two Additional ERC Starting Grants for Research on Stress and Stars

Two distinguished scientists at the Institute of Science and Technology Austria (ISTA) have been honored with prestigious European Research Council (ERC) Starting Grants of 1.5 million euros each, a remarkable accolade that underscores their promising research trajectories in the realms of neuroscience and astrophysics. These grants serve as vital support, enabling early-career scientists to establish their research teams, to investigate innovative ideas, and to lay the groundwork for potentially groundbreaking discoveries that could influence our understanding of complex biological and cosmic systems.

Among the recipients, Amelia Douglass, a neuroscientist originally from Australia, is set to focus her research on the multifaceted ways in which animals respond to stress. By examining both behavioral and physiological adaptations, Douglass aims to elucidate the mechanisms that underlie survival in the face of environmental challenges, such as predation, extreme temperatures, and infectious threats. Her prior experience as a postdoctoral research fellow at Harvard Medical School, coupled with her recent appointment at ISTA, paints a picture of a researcher poised to make significant contributions in her field.

Douglass’s project, titled “The hypothalamic control of behavioral and physiological adaptations to stress,” succinctly dubbed “HypoAdapt,” seeks to peel back the layers of complexity surrounding the brain’s role in stress responses. Mice will serve as the primary model organism for this research, as they provide an excellent analog for studying the intricacies of stress management in biological systems. Douglass’s research team will investigate how the brain orchestrates quick responses to threats while also probing the lasting effects that chronic stress may have on behavior and physiologic functions.

In her own words, Douglass states, “We want to understand the brain-driven adaptations to these threats at two different levels: First, we want to know how these responses are so rapidly executed when a challenge is encountered.” This research is of paramount importance not only for understanding animal behavior but also for exploring the implications for human health, particularly in individuals grappling with anxiety and stress-related disorders. The potential translational impact of this work underscores the relevance of her research to the broader fields of clinical psychology and neuroscience.

Beyond her immediate research goals, Douglass hopes to use the funding to expand her team, bringing additional postdoctoral fellows and PhD students on board. The financial backing from the ERC will allow her to explore more ambitious questions than she could otherwise undertake, fostering an environment of innovation and depth in her laboratory. Coupled with ISTA’s robust scientific infrastructure, the potential for significant discoveries increases exponentially, promising to unlock new insights into the ways that living organisms manage stress.

Parallel to Douglass’s promising endeavors, Ylva Götberg, an astrophysicist from Sweden, is embarking on her own ambitious journey, equipped with an ERC Starting Grant to investigate the intriguing phenomenon of binary-stripped stars. Currently, Götberg’s work is poised to reshape our understanding of stellar evolution. Her project, “The Role of Binary-Stripped Stars: from Atomic Scales to Cosmic Dawn,” unravels the dynamics of these celestial bodies that, until recently, were relegated to theoretical discussions.

To clarify, binary-stripped stars refer to pairs of stars wherein one star siphons the hydrogen-rich envelope from its partner, ultimately exposing the helium core. Götberg’s research holds the potential to fill a notable gap in stellar astrophysics, as it is estimated that nearly one-third of all massive stars will undergo this transformation. Importantly, these stripped stars are believed to play critical roles in the genesis of hydrogen-poor supernovae and are fundamental to our understanding of phenomena such as gravitational waves, which result from neutron star mergers.

Götberg’s journey has been remarkable, having completed her PhD in the Netherlands before completing a NASA Hubble Postdoctoral Fellowship in the United States. Her recent appointment to ISTA in 2023 represents a pivotal moment in her career, and her recognition as one of TIME magazine’s 100 Emerging Leaders in 2024 underscores her promise in the competitive field of astrophysics. She reflects on the groundbreaking research ahead, asserting, “With us having recently confirmed their existence, theoretical models can now face reality and observational benchmarks.”

By leveraging upcoming data from major space missions, such as the ultraviolet space telescope UVEX and the laser interferometer LISA for gravitational waves, Götberg and her team will explore the properties and behaviors of stripped binaries in unprecedented detail. The intersection of theory and observation will allow them to pose critical questions about the evolution of binary star systems and to gather vital metrics related to stellar winds and mass transfer efficiencies.

The success of ISTA stands as a testament to its exemplary research environment; since its inception in 2009, it has grown to become a beacon of scientific excellence in Europe. With a striking 47% success rate in securing ERC frontier grants—substantially higher than the broader average—ISTA produces a remarkable workforce of researchers, with 82% of its professors achieving at least one ERC grant. Such achievements spotlight the institute as a critical player in both national and international scientific landscapes.

As the world enters a new era of scientific exploration, the research undertaken by Douglass and Götberg signifies a critical intersection of neuroscience and astrophysics, uniting seemingly disparate scientific disciplines under the universal quest for knowledge. Their findings may not only unravel the complexities of animal behavior and cosmic phenomena but also provide much-needed insights into the profound questions surrounding life, survival, and the universe’s grand design.

Science knows no bounds, and the stories of Douglass and Götberg represent just the tip of the iceberg in our understanding of both animal and cosmic realms. As they embark on their respective projects, the scientific community eagerly anticipates the revelations that lie ahead, which may well alter our perceptions about stress, survival, and the intricate dance of celestial bodies shaping our universe.