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Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old

June 5, 2024
in Medicine
Cassandra Pierce
By Cassandra Pierce Scienmag Editorial Profile - Systems Neuroscience
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Normal ageing might be associated with increased blood-brain barrier permeability
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Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old

Associations between regional blood-brain barrier permeability, aging, and Alzheimer’s disease biomarkers in cognitively normal older adults

Credit: Denkinger et al., 2024, PLOS ONE, CC-BY 4.0 (

Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old

###

Article URL: 

Author Countries: USA

Funding: Research reported in this publication was supported by the National Institute On Aging of the National Institutes of Health under Award Number F31AG072872 and R01 AG080043. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.



Journal

PLoS ONE

DOI

10.1371/journal.pone.0299764

Article Title

Associations between regional blood-brain barrier permeability, aging, and Alzheimer’s disease biomarkers in cognitively normal older adults

Article Publication Date

5-Jun-2024

COI Statement

I have read the journal’s policy and the authors of this manuscript have the following competing interests: Dr. Jagust has served as a consultant to Clario, Lilly and Eisai. Dr. Baker consults for Genentech. There are no other disclosures. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Subject of Research: Medicine

Article Title: Associations between regional blood-brain barrier permeability, aging, and Alzheimer’s disease biomarkers in cognitively normal older adults

Article References: Original research article

Image Credits: AI Generated

DOI: Not provided

Keywords: Not provided

Cite Scienmag News

Cassandra Pierce. (June 5, 2024). Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old. Scienmag. https://scienmag.com/normal-ageing-might-be-associated-with-increased-blood-brain-barrier-permeability-in-regions-also-vulnerable-in-alzheimers-disease-in-small-study-comparing-healthy-brains-of-the-young-and-old/

Cassandra Pierce. "Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old." Scienmag, 5 June 2024, https://scienmag.com/normal-ageing-might-be-associated-with-increased-blood-brain-barrier-permeability-in-regions-also-vulnerable-in-alzheimers-disease-in-small-study-comparing-healthy-brains-of-the-young-and-old/. Accessed 3 September 2026.

Cassandra Pierce. "Normal ageing might be associated with increased blood-brain barrier permeability in regions also vulnerable in Alzheimer’s Disease, in small study comparing healthy brains of the young and old." Scienmag. June 5, 2024. https://scienmag.com/normal-ageing-might-be-associated-with-increased-blood-brain-barrier-permeability-in-regions-also-vulnerable-in-alzheimers-disease-in-small-study-comparing-healthy-brains-of-the-young-and-old/

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