Lost Tumour Suppressor on Chromosome 6q Drives Deadly Childhood Brain Cancer and Reveals a Drug Target
New research shows that loss of the tumour suppressor LATS1 on chromosome 6q drives Hippo pathway dysregulation in ultra-high-risk PFA ...
Tag: YAP
Scientists Uncover Hidden Protein Driver Behind Scarring Kidney Disease
New research reveals that the protein Annexin A1 drives kidney fibrosis by activating YAP signaling and suppressing autophagy in renal ...
Gut Protein Claudin-2 Revealed as a Hidden Defender Against Dangerous E. coli Infections
New research in Nature Communications shows that the tight-junction protein claudin-2 protects mice from Citrobacter rodentium infection and colitis by ...
Cell Death Clue: Ferroptosis Linked to Egg Cell Damage in Diminished Ovarian Reserve
New research links ferroptosis-associated oxidative stress in cumulus cells and weakened mitochondrial function in oocytes to diminished ovarian reserve in ...
New Immune Checkpoint Discovery Explains Why Gastric Cancers Ignore PD-1 Drugs
Researchers created a mouse model of refractory gastric cancer and discovered that the YAP-driven BST2 protein reprograms neutrophils and Kupffer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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