Gliding Mammals Evolved the Same Skill Through Different Genetic Routes
A genomic comparison of three independently evolved gliding mammal lineages shows that different regulatory DNA regions can converge on similar ...
Tag: Wnt signaling
Sugar Metabolism Emerges as a Master Switch Controlling Bone Rebuilding
A new review argues that glycolysis acts as a signaling hub in bone remodeling, with glycolytic enzymes and metabolites such ...
New Spatial Transcriptomics Tool Maps Gene Expression Across Tissue Boundaries in the Developing Mouse Brain
Researchers have developed REBOSEP, a computational workflow that maps gene expression as a continuous signal across tissue boundaries and reveals ...
Aging Disc Cells Lose a Key Signal That Calls Immune Cells to Heal Injured Spines
New research in mice shows that age-related loss of Wnt signaling in intervertebral disc cells suppresses chemokine production and blunts ...
Loss of a Single Protein Derails Brain Development and Drives Autism-Like Behavior in Mice
New research shows that the protein UBAP2L is essential for neural progenitor cell division, and that its loss in mice ...
A Hidden RNA Switch May Shape Cashmere Goat Hair Follicles Before Birth
Researchers in Inner Mongolia have identified a cytoplasmic long non-coding RNA, MSTRG.18075.2, that peaks at embryonic day 55 in cashmere ...
Touch-Sensing Piezo Channels Found to Steer the Cells That Build Our Teeth
Researchers at the University of Maryland Baltimore have shown that the mechanosensitive ion channels Piezo1 and Piezo2 drive the terminal ...
A Tiny Glycine Repeat May Have Helped Mammals Grow Hair, Study Suggests
Researchers report that a polyglycine repeat inserted into the Hoxc13 transcription factor during mammalian evolution dramatically expanded its genome-wide DNA ...
Chemical Tags on RNA May Steer a Sheep’s Dramatic Black-to-White Coat Change
Integrated sequencing of RNA chemical modifications and gene expression reveals candidate m6A-tagged genes linked to the developmental shift from black ...
TFEB Drives Rare Kidney Cancer Growth Through a Long Non-Coding RNA Relay
New research reveals that the Alpha-TFEB fusion gene drives t(6;11) translocation renal cell carcinoma by activating the long non-coding RNA ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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