Zika Virus Splits One Protein Into Two Forms With Opposing Jobs in Its Life Cycle
New research in PLOS Pathogens shows that Zika virus produces two isoforms of the NS2A protein, with the full-length form ...
Tag: virology
Silencing HPV16 Oncogenes E5 and E6 Emerges as a Promising Route Against Cervical Cancer
A new review in Virology Journal examines how siRNA and CRISPR/Cas gene-silencing technologies could target the HPV16 oncoproteins E5 and ...
Pet Rats Suspected in First Human Cowpox Cases Recorded in Czech Republic
The first documented human cowpox infections in the Czech Republic affected two young adults whose pet rats died of respiratory ...
Fatty Liver Cells Turn On a Caspase-2 Death Pathway That Damps Hepatitis B Replication
New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic pathway that is associated with reduced ...
Tick-Borne SFTS Virus: New Review Maps How Multi-Organ Failure Kills
A comprehensive new review synthesizes the direct viral and immune-mediated mechanisms driving multi-organ failure in severe fever with thrombocytopenia syndrome, ...
Fish Cell Lines Move Beyond the Petri Dish to Drive Biotech, Toxicology and Disease Research
A new review charts how six decades of fish cell line development, from the 1962 RTG-2 breakthrough to CRISPR-edited cultures, ...
Flu Virus Protein NS2 Sabotages Interferon Alarm by Hijacking Host Ubiquitin Regulator UBL7
New research shows that influenza A virus protein NS2 suppresses type I interferon signaling by competing with MAVS to bind ...
Virulent Newcastle Disease Virus Subgenotype VII.1.1 Behind 2025 Poultry Outbreak in Southern Peru, Whole-Genome Study Finds
Whole-genome sequencing of isolates from a 2025 commercial poultry outbreak in southern Peru identified a genetically homogeneous, virulent Newcastle disease ...
Cryo-ET Captures Molecular Movie of Rotavirus Punching Into Cells
Harvard Medical School researchers used cryo-electron tomography to reveal how rotavirus VP7 forms a membrane pore that delivers the viral ...
SARS-CoV-2 Enzyme NSP14 Disrupts DHX15-RIG-I Partnership to Silence Antiviral Alarm
New research shows that the SARS-CoV-2 enzyme NSP14 suppresses interferon production by binding the helicase DHX15 and disrupting its cooperative ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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