Editors Flag Image Concerns in Study Linking Aurora Kinase A Pathway to Leukemia Drug Resistance
The Journal of Experimental & Clinical Cancer Research has issued an editorial expression of concern over image integrity in a ...
Tag: Tyrosine kinase inhibitors
Circular RNA Culprit Behind Imatinib Failure in Leukemia Identified
Researchers in China have identified a circular RNA, hsa_circ_0029325, that drives imatinib resistance in chronic myeloid leukemia by upregulating the ...
The Fibroblast Problem: Why Liver Cancer Drugs So Often Fail
A new review identifies three fibroblast-driven mechanisms that make liver cancer cells resistant to kinase inhibitors and immunotherapy, while warning ...
Right-Sizing HER2-Positive Breast Cancer Treatment: New Algorithms Reshape Care Across the Disease Continuum
A new Nature Reviews Clinical Oncology review charts how HER2-targeted therapies, led by trastuzumab deruxtecan, are driving a shift from ...
Under the Microscope: Tumor Invasion Grading Predicts Survival After Liver Cancer Conversion Therapy
A multicenter study shows that grading the severity of microvascular invasion in resected liver tumors strongly predicts recurrence and survival ...
Life After the Pill: Real-World Quality of Life Across CML Drugs and Treatment-Free Remission
A nationwide Israeli survey of 233 CML patients finds overall quality of life is preserved across tyrosine kinase inhibitors, but ...
Two-Drug Combo Supercharges Liver Cancer Therapy in Preclinical Study
A preclinical study reports that combining the kinase inhibitor regorafenib with the small-molecule PD-1/PD-L1 inhibitor BMS-1 synergistically suppresses the growth, ...
Asciminib Shows Strong Real-World Results in Hard-to-Treat Leukaemia Patients
A six-patient Italian real-world case series reports that asciminib achieved sustained molecular responses and a favourable cardiovascular safety profile in ...
Bacteria Inside Liver Tumors May Predict Who Responds to Cancer Conversion Therapy
Researchers found that liver cancer patients who responded poorly to conversion therapy harbored distinct bacterial communities inside their tumors, including ...
Immunotherapy Reshapes Advanced Liver Cancer Care in Europe, but Access Lags Behind
A major Lancet Regional Health – Europe review charts how combination immunotherapy transformed advanced hepatocellular carcinoma treatment while exposing stark ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!