Aberrant Myelopoiesis Precedes Sex-Dependent Cancer Cachexia Onset in Mice
A mouse study found that sex-dependent bone-marrow and stem-cell-niche remodelling preceded severe muscle loss in males with cancer cachexia.
Tag: tumour immunology
Blood Test Clue: Immune Cells That Betray Early Lung Cancer Before It Strikes
Researchers have discovered a clonally coordinated network of suppressive regulatory T cells that spans the blood, lymph nodes and airways ...
Tiny vesicles in cancer patients’ blood rewire T cells and blunt immunity
Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression ...
Gamma Delta T Cells Blur the Line Between Innate and Adaptive Immunity
New research in Nature shows that gamma delta T cells rely on their adaptive T cell receptors in real time ...
Dogs’ Insulin-Secreting Tumors Reveal Two Hidden Cancer Cell Types in First-of-Its-Kind Study
The first single-cell RNA sequencing study of naturally occurring insulinoma in any species reveals two distinct insulin-expressing cancer cell populations, ...
Gut Microbes Prime Regulatory B Cells That Shape Cancer Immunotherapy Outcomes
A new review explains how gut microbes program immunosuppressive regulatory B cells through cytokine and metabolite signals, with major implications ...
New Spatial Index Measures the Immune Barrier That Shields Tumours From Attack
Researchers have introduced the Spatial Immune Barrier Index, a spatial transcriptomics measure that quantifies the suppressive barrier holding immune cells ...
Immune Cells Inside Breast Tumours May Signal Spread to Lymph Nodes
A Malaysian study of 241 early breast cancer patients finds that higher levels of tumour-infiltrating lymphocytes are linked to lower ...
Proximity-guided graph learning reveals tumour-associated proximity antigens
The concept of a proximity antigen sits at an important intersection of tumour immunology, spatial biology, and machine learning, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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