Lysosome Gene Signature Offers New Prognostic Tool for Lung Cancer
Researchers have built a 13-gene lysosome-related signature that predicts survival, immune landscape, and drug responses in lung adenocarcinoma patients.
Tag: tumor mutation burden
Mitochondrial Gatekeeping Genes Offer New Way to Predict Lung Cancer Survival
A machine-learning model built on seven genes tied to mitochondrial outer membrane permeabilization stratifies lung adenocarcinoma patients into distinct survival ...
DNA Repair Gene Mutations Predict Dramatically Better Immunotherapy Outcomes in Colorectal Cancer
A study of 450 colorectal cancer patients shows that POLE and POLD1 proofreading gene mutations predict markedly better immunotherapy response ...
Fat-Fueled RNA Signals Predict Survival and Drug Response in Lung Cancer
A new integrative study identifies three lipid metabolism-related long non-coding RNAs that predict survival, immune landscape, and drug sensitivity in ...
Dogs and Humans Share Genetic Drivers of Liver Cancer, First Multi-Omics Study Reveals
A first-of-its-kind multi-omics study shows that dogs and humans share key genetic drivers and conserved tumor microenvironment features in hepatocellular ...
Space Radiation Leaves Distinct Mutational Fingerprints in Mouse Liver Tumors
Whole genome sequencing of liver tumors in outbred mice reveals distinct mutational fingerprints of heavy-ion and gamma-ray radiation, including frequent ...
Small Cell Lung Cancer Relies on Targetable Nonsense-Mediated Decay for Immune Control
A Hidden RNA-Decay System May Be the Achilles’ Heel of Small-Cell Lung Cancer Small-cell lung cancer, one of the most ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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