Researchers have identified an energy-stress-induced long non-coding RNA called GIRGL that drives glucose metabolism reprogramming in lung adenocarcinoma by interacting ...
A new mouse study finds that combining the PARP inhibitor olaparib with radiotherapy improves tumor control in oral squamous cell ...
A new review synthesizes decades of evidence showing that selective COX-2 inhibitors can suppress tumor initiation, growth and immunotherapy resistance ...
Colorectal cancer has long been divided into two camps at the genetic level: tumors carrying mutations in the KRAS gene ...
A single intratumoral injection of the experimental TLR4 agonist EmT4™ transformed an immunologically quiet canine soft tissue sarcoma into an ...
A new review explains how radiation-induced CCL2/CCR2 signaling recruits immunosuppressive myeloid cells and remodels the tumor microenvironment, and why combining ...
A new computational platform reveals how collagen architecture and myeloid cells cooperate to trap therapeutic T cells in pancreatic tumors, ...
In a discovery that may finally explain one of the most confounding paradoxes in cancer biology, researchers at the Salk ...
Cellular senescence has long been one of biology's most paradoxical phenomena. In healthy tissue, senescent cells—those that have permanently exited ...
Brain metastases strike up to 30 percent of cancer patients, bringing headaches, seizures, neurological deficits and a median survival of ...
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