Laser-Dissected Proteomics Reveals Where Immunity Really Lives in Triple-Negative Breast Tumors
A new spatial proteomics study shows that immune activity in triple-negative breast cancer is concentrated in the tumor stroma rather ...
Tag: tumor microenvironment
Self-Sustaining Nanoplatform Starves Tumors and Unleashes Four-Way Cancer Therapy
A new biodegradable nanoparticle called HILA continuously drains tumors of lactate while orchestrating starvation, chemodynamic, photodynamic, and photothermal therapy against ...
AI Learns to Read Cancer Slides Like a Pathologist by Watching the Neighborhood
Researchers in China have developed a neighbor-constrained attention framework that improves how artificial intelligence classifies gigapixel whole-slide pathology images by ...
Young Dogs With Splenic Cancer Live Far Longer on Chemotherapy, Landmark Trial Reveals
A phase I trial of propranolol plus doxorubicin found no survival benefit from the beta-blocker, but revealed that young adult ...
Blood-Brain Barrier Leaks Distort Brain Tumor PET Scans, Mouse Study Reveals
A mouse study shows that TSPO-PET signals in glioblastoma remain largely cell-specific early on but lose specificity as blood-brain barrier ...
CAR-T Cell Therapy Pushes Beyond Blood Cancers Into Solid Tumors and Autoimmune Disease
A sweeping review charts how CAR-T cell therapy has evolved from a blood cancer breakthrough into a versatile platform tackling ...
Scientists Map a Hidden Malignant Program in Triple-Negative Breast Cancer
An integrated single-cell and spatial transcriptomic study has identified a triple-negative breast cancer-enriched malignant epithelial program, EP5, linked to aggressive ...
Collagen Receptor CD49b Emerges as Key Switch That Lets Breast Tumors Hide From Immunotherapy
Blocking the collagen receptor integrin alpha-2 (CD49b) on breast cancer cells remodels the tumor immune microenvironment and synergizes with anti-PD-L1 ...
How Tumor Stiffness May Rewire RNA Chemistry to Help Cancers Evade Immunity
A new review in Molecular Cancer proposes that mechanical forces within tumors can reprogram RNA modifications, offering a fresh framework ...
Anxiety and Depression May Blunt Immunotherapy Response in Stomach Cancer Patients
A multicentre retrospective cohort study finds that gastric cancer patients with emotional distress show markedly poorer pathological response to neoadjuvant ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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