Macrophage Exosomes Disarm Immune Cells and Fuel Ovarian Cancer Spread
A new study shows that exosomes released by tumor-associated macrophages carry PD-L1 that reprograms the metabolism of CD8-positive T cells, ...
Tag: tumor microenvironment
Blocking a Magnesium-Sensing RNA Shredder Makes Cancer Immunotherapy Work Better
Xiamen University researchers report that inhibiting RNASET2, a magnesium-sensitive enzyme that clears mitochondrial double-stranded RNA, ignites innate immune signaling in ...
AI Maps How Deadly Childhood Brain Tumors Outsmart Treatment
A new review in the Journal of Neuro-Oncology details how machine learning and computational frameworks applied to single-cell and spatial ...
Radiation Supercharges Natural Killer Cell Therapy Against Liver Cancer in New Study
New research shows that radiation can make liver cancer cells more visible to natural killer cells, boosting the effectiveness of ...
AI Knockout Screen Reveals GSTP1 as a Driver of Lung Cancer Immunotherapy Resistance
A transformer-based in-silico gene knockout screen across 109 cell types has identified GSTP1 as a key driver of immunotherapy resistance ...
Engineered Immune Cells Push Melanoma Therapy Into a New Era
A new review details how tumor-infiltrating lymphocyte, CAR-T, and TCR-engineered cell therapies are transforming melanoma treatment and the engineering breakthroughs ...
Bacteria Inside Liver Tumors May Predict Who Responds to Cancer Conversion Therapy
Researchers found that liver cancer patients who responded poorly to conversion therapy harbored distinct bacterial communities inside their tumors, including ...
Biophysicist Kandice Tanner Wins 2027 Bárány Award for Metastasis Discoveries
The Biophysical Society will honor National Cancer Institute biophysicist Kandice Tanner with the 2027 Michael and Kate Bárány Award for ...
From Bench to Bedside: New Tools Push Veterinary Oral Cancer Toward Targeted Therapy
New spatial transcriptomics, patient-derived models, and comparative clinical trials of trametinib and a STAT3 decoy are transforming the treatment of ...
Synthetic antibody fragment lights up human macrophages in PET scans
Researchers have developed the first immunoPET tracer targeting human CD68, a synthetic zirconium-89-labeled antibody fragment that visualized macrophages in mouse ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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