Tag: tumor microenvironment

University of Oklahoma researchers have identified three adjacent cell subclusters in pancreatic tumors that form a feed-forward network driving cancer ...

A new review proposes co-designing oncolytic viruses and CAR-T or CAR-NK cells as a modular, self-amplifying therapeutic system to overcome ...

A new review maps how cancer-associated fibroblasts exclude immune cells from osteosarcoma tumors and outlines the therapeutic strategies that could ...

A new review describes how NMDA glutamate receptors on myeloid cells drive calcium-dependent reprogramming toward immunosuppressive states, and how blocking ...

Researchers have engineered a 3D-printed hydrogel scaffold that kills residual bone tumor cells through pH-responsive nanozyme catalysis, activates antitumor immunity ...

Researchers have developed and validated a 45-gene transcriptomic signature, Met-Score, that quantifies metastatic competence in primary prostate tumors and predicts ...

A new computational framework called CellART unifies cell segmentation and cell-type annotation across high-resolution spatial transcriptomics platforms, revealing single-cell detail ...

A new review in the Journal of Translational Medicine argues that c-MET signaling shapes spatially confined, metabolically driven immunosuppressive niches ...

A large-scale proteomic study of 404 cervical cancer samples has revealed three molecular subtypes of squamous cell carcinoma with distinct ...

A new review synthesizes clinical trial evidence showing that combining radiotherapy with immune checkpoint inhibitors can dramatically boost response rates ...