Review maps cancer-linked BCAA rewiring in muscle
A review finds that cancer redirects branched-chain amino acid metabolism in a tissue- and tumor-dependent manner, contributing to muscle wasting ...
Tag: tumor metabolism
Machine learning links PDF to cold colorectal cancer
A machine-learning and proteomics study associates high peptide deformylase expression with immune-cold colorectal cancer, low immune infiltration, elevated oxidative phosphorylation ...
Review frames microbiome–mitochondria crosstalk in glioblastoma research
A review frames microbiome-derived metabolites and mitochondrial activity as a proposed research axis for glioblastoma metabolism and immunity, while noting ...
SWAP70 promotes liver cancer growth through CPT1A-dependent fatty acid oxidation
Cell, tissue and mouse experiments link elevated SWAP70 to advanced human liver tumors and show that it supports hepatocellular carcinoma ...
Turning Off a Cancer Cell’s Survival Switch: How NRF2 Controls Ferroptosis in Targeted Therapy
A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...
Dietary supplement Ca-αKG slows lung tumors in female mice but speeds growth in males, UCLA study finds
A UCLA study found that the dietary supplement calcium alpha-ketoglutarate slowed lung tumor growth in female mice while enlarging tumors ...
Glioblastoma Pipeline Shifts to Biomarker-Guided Combination Therapies
A new Oncoscience perspective maps the 2025–2026 glioblastoma clinical trial pipeline across four mechanistic domains, showing how biomarker-guided selection and ...
PET Scan Glycolysis Measure Predicts Survival in EGFR-Mutant Lung Cancer on Targeted Therapy
A baseline PET/CT scan's SUVmax independently predicts progression-free survival in EGFR-mutant lung adenocarcinoma patients treated with tyrosine kinase inhibitors.
Gated Nanoreactor Turns Tumor Glucose Into Carbon Monoxide to Boost Mild Heat Therapy
A ZIF-8-gated cascade nanoreactor converts tumor glucose into hydrogen peroxide and carbon monoxide, depleting ATP and suppressing HSP70 so that ...
Mitochondrial DNA Copy Number Emerges as a Key Player in Cancer Progression
New research in The FEBS Journal links mitochondrial DNA copy number in cancer cells to mutational load, tumor growth gene ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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