PET Scans and Tumor Immunity: New Study Probes the Hidden Link in Breast Cancer
An exploratory study of 61 breast cancer patients found only weak, statistically fragile links between regional tumor immune-stromal composition and ...
Tag: tumor-infiltrating lymphocytes
Hidden armies inside glioblastoma: exhausted T cells hint at new immunotherapy routes
Single-cell analysis of 56 glioblastoma tumors reveals that T-cell-rich cases harbor clonally expanded, LAG3-high CD8 T cells that may be ...
IDO1 Inhibitor Plus Melanoma Vaccine Fails to Boost Tumor-Fighting T Cells in Trial
A phase II pilot trial found that the IDO1 inhibitor epacadostat safely reduced kynurenine-to-tryptophan ratios in advanced melanoma patients but ...
Chemotherapy-Free Drug Combo Shows Promise for Early Triple-Negative Breast Cancer
A phase II trial found that neoadjuvant camrelizumab plus apatinib, a chemotherapy-free combination of immunotherapy and anti-angiogenic therapy, produced manageable ...
DNA Repair Gene Mutations Predict Dramatically Better Immunotherapy Outcomes in Colorectal Cancer
A study of 450 colorectal cancer patients shows that POLE and POLD1 proofreading gene mutations predict markedly better immunotherapy response ...
Engineered Immune Cells Push Melanoma Therapy Into a New Era
A new review details how tumor-infiltrating lymphocyte, CAR-T, and TCR-engineered cell therapies are transforming melanoma treatment and the engineering breakthroughs ...
Laser-Dissected Proteomics Reveals Where Immunity Really Lives in Triple-Negative Breast Tumors
A new spatial proteomics study shows that immune activity in triple-negative breast cancer is concentrated in the tumor stroma rather ...
Immune Cells Cluster, Not Crowd, in Melanoma That Spreads to the Brain
A Dutch study finds that melanoma brain metastases harbor far fewer but more tightly clustered immune cells than other metastases, ...
Interleukin-2 emerges as both engine and saboteur in tumor-infiltrating lymphocyte therapy
A new review details how interleukin-2 both powers and undermines tumor-infiltrating lymphocyte therapy, and how engineered alternatives may finally break ...
Immune Cells Inside Breast Tumours May Signal Spread to Lymph Nodes
A Malaysian study of 241 early breast cancer patients finds that higher levels of tumour-infiltrating lymphocytes are linked to lower ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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