Mogrosides regulate tumor metabolism and immune response, revealing dual anticancer mechanism
The monk fruit, a small green gourd native to the mountainous forests of Guangxi province in southern China, has been ...
Tag: Tumor Immune Evasion
Small Cell Lung Cancer Relies on Targetable Nonsense-Mediated Decay for Immune Control
A Hidden RNA-Decay System May Be the Achilles’ Heel of Small-Cell Lung Cancer Small-cell lung cancer, one of the most ...
USP30-AS1 micropeptide drives tumor growth by suppressing macrophage cGAS–STING interferon signaling
Immune checkpoint inhibitors have transformed cancer treatment by releasing molecular brakes that otherwise restrain T cells, yet their benefits remain ...
Engineered macrophages reprogram tumor microenvironments, boosting antitumor immunity with IL-10–TLR9 switches
Cancer immunotherapy has transformed treatment for some patients, yet many solid tumors remain protected by a hostile biological environment that ...
Early Trial Tests Ontorpacept Plus Doxorubicin for Advanced Leiomyosarcoma
A new Phase 1/2 clinical study is testing whether an immune-targeting drug can make chemotherapy more effective against high-grade leiomyosarcoma, ...
How tumors evade immunotherapy: DDB1 sends PD-L1 into nuclei, driving anti-PD-1 resistance
Immune checkpoint blockade has reshaped modern oncology, but its success remains uneven. Drugs that disrupt the PD-1/PD-L1 pathway can produce ...
KRAS inhibitors MRTX1133 or daraxonrasib synergize with anti-CTLA4 in pancreatic cancer
A new viral-science report highlights fresh evidence that directly targeting oncogenic KRAS can prime the immune system to fight pancreatic ...
Tremelimumab Plus Paclitaxel in Metastatic Urothelial Cancer
In a groundbreaking advancement in the treatment of metastatic urothelial cancer, a recent clinical trial has explored the synergistic potential ...
Cancer Hijacks Mitochondria to Paralyze Immune Attack
In a dramatic revelation that challenges conventional thinking about cell biology, scientists report that cancer cells can effectively “poison” the ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!